Results 51 to 60 of about 96,265 (294)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Simplifying Administration of Health Insurance [PDF]
, 2008 Reviews definitions and estimates of the insurance system's administrative costs and efforts to reduce them. Examines the potential of various reform proposals to simplify or further complicate the system.
core
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Provider Behavior Under Global Budgeting and Policy Responses [PDF]
Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2015 Third-party payer systems are consistently associated with health care cost escalation. Taiwan’s single-payer, universal coverage National Health Insurance (NHI) adopted global budgeting (GB) to achieve cost control. This study
Chao-Kai Chang MD, PhD +6 more
doaj +1 more source
The Regulatory Component of Health Care Reform [PDF]
, 2008 Explains the rationales and goals of regulatory intervention. Assesses the likelihood that proposed changes to regulations will be implemented as a component of healthcare reform or that they will help control costs and improve ...
Roger G. Noll
core
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Identification of the Main Elements of Single Payer System; A Comparative Study
Journal of Evidence Based Health Policy, Management & Economics, 2019 Background: Progress towards universal coverage requires adequate capital in health sector. Investing and optimal allocation of resources in this sector will contribute to the development and reduction of poverty in countries in order to achieve the ...
Ali Aboutorabi +3 more
doaj
Severing the Tie That Binds: Why a Publicly Funded, Universal Health Care System Would Be a Boon to U.S. Businesses [PDF]
, 2014 Americans' dependence on employer-sponsored health insurance arose as an unintended byproduct of World War II economic controls. To circumvent wage caps, businesses began offering health insurance and other fringe benefits to attract workers. The federal
Taylor Lincoln
core
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source