Results 151 to 160 of about 2,447,201 (267)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Single-phase full-bridge inverter control based on discrete adaptive sliding mode algorithm with error compensation. [PDF]

PLoS One
Zhang Y, Tang Z, Xu F, Zhou K, Yang K.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Fault Diagnosis and Location Method for Stator-Winding Single-Phase Grounding of Large Generator Based on Stepped-Frequency Pulse Injection. [PDF]

Sensors (Basel)
Lei B, Xu S, Liu Y, Zu W, Yu M, Guo Y, Dong L, Cheng Z.   +7 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

A symmetric single phase diode assisted dual boost Z-source switched capacitor seven level inverter with modified SPWM. [PDF]

Sci Rep
Hosseini S, Hosseini SH, Sabahi M, Khounjahan H, Nadermohammadi A.   +4 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Single-Phase Lithiation in Iron Hydroxy Fluorides with Pyrochlore Structure. [PDF]

ACS Energy Lett
Baumgärtner JF, Stoian DC, Marshall KP, Jafarpour M, Klimpel M, Zhang H, Okur F, van Beek W, Chernyshov D, Abdolhosseinzadeh S, Wörle M, Kovalenko MV, Kravchyk KV.   +12 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Prediction of Magnetic Fields in Single-Phase Transformers Under Excitation Inrush Based on Machine Learning. [PDF]

Sensors (Basel)
Peng Q, Du H, Zheng Z, Zhu H, Fang Y.
europepmc   +1 more source