Results 111 to 120 of about 3,832,000 (370)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Research Progress of Microchannel Heat Sink Structures Based on Single-Phase Flow

open access: yesZhileng xuebao
Microchannel cooling, with its high heat transfer efficiency, low thermal resistance, and light weight advantages, is one of the most effective technologies for solving the problem of heat dissipation with high heat flux; however, it faces the issue of ...
Zhao Jie, Cui Xiaoyu
doaj  

Statistical mechanics of non-hamiltonian systems: Traffic flow

open access: yes, 2007
Statistical mechanics of a small system of cars on a single-lane road is developed. The system is not characterized by a Hamiltonian but by a conditional probability of a velocity of a car for the given velocity and distance of the car ahead ...
A Šurda   +10 more
core   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

High-performance monoliths in heterogeneous catalysis with single-phase liquid flow

open access: yes, 2017
Hierarchical, macro-mesoporous silica monoliths with domain sizes (sum of mean macropore size and skeleton thickness) of ∼1 μm are highly efficient supports in heterogeneous catalysis with single-phase liquid flow.
Christian P. Haas   +4 more
semanticscholar   +1 more source

Quantum phase transition of Ising-coupled Kondo impurities

open access: yes, 2004
We investigate a model of two Kondo impurities coupled via an Ising interaction. Exploiting the mapping to a generalized single-impurity Anderson model, we establish that the model has a singlet and a (pseudospin) doublet phase separated by a Kosterlitz ...
A. C. Hewson   +17 more
core   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Fluidelastic instability of a curved tube array in single phase cross flow

open access: yesNuclear Engineering and Technology, 2023
Experimental study on the fluidelastic instability (FEI) of a curved tube bundle in single phase downward cross flow is investigated for the design qualification and analysis input preparation of helical coiled steam generator tubing. A 6x9 normal square
Kang-Hee Lee   +3 more
doaj  

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