Results 111 to 120 of about 2,116,123 (314)

Impact of Rock Cuttings on Downhole Fluid Movement in Polycrystalline Diamond Compact (PDC) Bits, Computational Fluid Dynamics, Simulation, and Optimization of Hydraulic Structures

open access: yesFluids
The flow occurring at the bottom of a polycrystalline diamond compact (PDC) drill bit involves a complex process made up of drilling fluid and the drilled rock cuttings.
Lihong Wei, Jaime Honra
doaj   +1 more source

Single-Phase Heat Transfer and Fluid Flow Phenomena of Microchannel Heat Exchangers

open access: hybrid, 2012
Thanhtrung Dang   +6 more
openalex   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Improved pore network models to simulate single-phase flow in porous media by coupling with lattice Boltzmann method

open access: hybrid, 2020
Jianlin Zhao   +4 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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