Results 151 to 160 of about 3,832,000 (370)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Assessment of MARS-KS prediction capability for natural circulation flow in passive heat removal system

open access: yesNuclear Engineering and Technology
Considering that system analysis codes are used for the evaluation of the performance of Passive Safety Systems (PSSs), it is important to investigate the capability of the system analysis code to reliably predict the heat transfer and natural ...
Jehee Lee   +4 more
doaj  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Numerical Analysis of Performance Deterioration of a Centrifugal Pump Operating in Two-Phase Flows

open access: yesJournal of Applied Fluid Mechanics, 2019
Pumps handling two-phase flows are essential parts of industrial process mainly in oil and gas facilities and power plants. It is known that for centrifugal pumps the presence of gas phase in liquid flow causes the performance to deteriorate.
A. Atif, S. Senouci
doaj  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy