Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha+6 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Feasibility analysis of neutral grounding by small reactor of HVDC converter transformer
Nowadays, the scale of power grid is remarkably increasing and there is a continuous reinforcement of AC–DC hybrid systems. Thus, the single-phase grounding fault currents on the AC grid-side of rectifier and inverter stations increase significantly ...
Ensheng Zhao+5 more
doaj
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
Analisa Penggunaan Over Current Relay (OCR) Sebagai Alat Proteksi Pada Transformator Daya Gardu Induk Sekarputih PT.PLN (PERSERO) [PDF]
in the data at the Sekar Putih substation on a single side 70 kV transformer the short circuit disturbance is 14,505 kA for three phases and 0.647 kA for one phase to ground, while on the 150 kV side the three phase short circuit disturbance is 21,501 kA
Irfansyah, Mohammad Afif, Wati, Trisna
core +2 more sources
A novel traveling-wave-based method improved by unsupervised learning for fault location of power cables via sheath current monitoring [PDF]
In order to improve the practice in maintenance of power cables, this paper proposes a novel traveling-wave-based fault location method improved by unsupervised learning.
Li, Mingzhen+4 more
core +1 more source
ABSTRACT Dopaminergic medication and deep brain stimulation (DBS) improve motor symptoms in Parkinson's disease (PD), but levodopa response alone may not predict DBS outcomes. We retrospectively analyzed 19 PD patients undergoing levodopa challenges with and without prior transcranial direct current stimulation targeting a defined PD response network ...
Lukas L. Goede+3 more
wiley +1 more source
Faults and unbalance forces in the switched reluctance machine [PDF]
The paper identifies and analyzes a number of severe fault conditions that can occur in the switched reluctance machine, from the electrical and mechanical points of view.
Miller, T.J.E.
core +1 more source
Mechanisms of De‐icing by Surface Rayleigh and Plate Lamb Acoustic Waves
Ice accretion impacts daily life, renewable energy generation, maintenance, and security in industries and aeronautics. Acoustic waves (AW) are a promising method for ice removal, although de‐icing mechanisms require further investigation to optimize energy efficiency.
Shilpi Pandey+15 more
wiley +1 more source
Hybrid materials enable high‐performance components but are challenging to process. This study explores an inductive heating concept with spray cooling for steel–aluminum specimens in a two‐step process including friction welding and cup backward extrusion.
Armin Piwek+7 more
wiley +1 more source