Results 41 to 50 of about 18,660,610 (240)
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Macroplastics, defined as plastic debris ranging from 2.5 to 100 cm, pose significant threats to aquatic ecosystems, as they can breakdown into smaller particles.
Adinda P.A. Nevandhra +3 more
doaj +3 more sources
An Overview of Plastic Waste Generation and Management in Food Packaging Industries
Over the years, the world was not paying strict attention to the impact of rapid growth in plastic use. This has led to unprecedented amounts of mixed types of plastic waste entering the environment unmanaged.
Lindani Koketso Ncube +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Plastics in the Circular Economy
The circular economy focuses on the issue of low use of materials. In a circular economy, the value of products and materials is preserved for as long as possible, waste and resource use are minimised, and resources do not leave the economic flow once ...
Elena-Loredana Pîrvu
doaj
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
This paper analyses the coverage and socio-contextual representation of the single-use plastics ban by two mainstream newspapers in Malawi, The Daily Times and The Nation Newspapers, between January 2019 and December 2022.
Victor Chikaipa
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Waste Plastic, the Challenge Facing Developing Countries—Ban It, Change It, Collect It?
With changing consumption patterns, growing populations and increased urbanisation, developing countries face significant challenges with regards to waste management.
Linda Godfrey
doaj +1 more source
Transportation fate and removal of microplastic pollution – A perspective on environmental pollution
With ever-increasing environmental pollution concerns, at large, and microplastic pollution, in particular, a sustainable quantification and redefining of plastic pollution is required urgently.
Muhammad Bilal, Hafiz M.N. Iqbal
doaj +1 more source

