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Single-cell phylotranscriptomics of developmental and cell type evolution

Trends in Genetics
Single-cell phylotranscriptomics is an emerging tool to reveal the molecular and cellular mechanisms of evolution. We summarize its utility in studying the hourglass pattern of ontogenetic evolution and for understanding the evolutionary history of cell types. The developmental hourglass model suggests that the mid-embryonic stage is the most conserved
Fuqiang Ma, Chaogu Zheng
openaire   +2 more sources

Single-cell messenger RNA sequencing reveals rare intestinal cell types

Nature, 2015
Understanding the development and function of an organ requires the characterization of all of its cell types. Traditional methods for visualizing and isolating subpopulations of cells are based on messenger RNA or protein expression of only a few known marker genes.
Dominic Grün   +7 more
openaire   +3 more sources

Efficient Matching of Single Cells and Cell Types

2022 IEEE 10th International Conference on Healthcare Informatics (ICHI), 2022
Primoz Godec   +3 more
openaire   +1 more source

LINNAEUS: Simultaneous Single-Cell Lineage Tracing and Cell Type Identification

A key goal of biology is to understand the origin of the many cell types that can be observed during diverse processes such as development, regeneration, and disease. Single-cell RNA-sequencing (scRNA-seq) is commonly used to identify cell types in a tissue or organ.
Bastiaan, Spanjaard, Jan Philipp, Junker
openaire   +2 more sources

Integrated analysis of multimodal single-cell data

Cell, 2021
Yuhan Hao   +2 more
exaly  

Single-cell atlases: shared and tissue-specific cell types across human organs

Nature Reviews Genetics, 2022
Rasa Elmentaite   +2 more
exaly  

An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma

Ca-A Cancer Journal for Clinicians, 2022
Elshad Hasanov   +2 more
exaly  

Understanding tumour endothelial cell heterogeneity and function from single-cell omics

Nature Reviews Cancer, 2023
Qun Zeng, Mira Mousa, Halima Alnaqbi
exaly  

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