Results 71 to 80 of about 3,562,031 (294)

scCATCH: Automatic Annotation on Cell Types of Clusters from Single-Cell RNA Sequencing Data

open access: yesiScience, 2020
Summary: Recent advancements in single-cell RNA sequencing (scRNA-seq) have facilitated the classification of thousands of cells through transcriptome profiling, wherein accurate cell type identification is critical for mechanistic studies.
Xin Shao   +5 more
doaj   +1 more source

Single cell electroporation on chip [PDF]

open access: yes, 2006
In this thesis the results of the development of microfluidic cell trap devices for single cell electroporation are described, which are to be used for gene transfection.
Valero, Ana
core   +2 more sources

Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death [PDF]

open access: yes, 2016
Sensing bacterial products in the cytosol of mammalian cells by NOD-like receptors leads to the activation of caspase-1 inflammasomes, and the production of the pro-inflammatory cytokines interleukin (IL)-18 and IL-1β.
Alix, E   +7 more
core   +1 more source

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi   +20 more
wiley   +1 more source

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges   +12 more
wiley   +1 more source

HArmonized single-cell RNA-seq Cell type Assisted Deconvolution (HASCAD)

open access: yesBMC Medical Genomics, 2023
Abstract Background Cell composition deconvolution (CCD) is a type of bioinformatic task to estimate the cell fractions from bulk gene expression profiles, such as RNA-seq. Many CCD models were developed to perform linear regression analysis using reference gene expression signatures of distinct cell types.
Yen-Jung Chiu   +2 more
openaire   +3 more sources

gCAnno: a graph-based single cell type annotation method [PDF]

open access: yesBMC Genomics, 2020
Abstract Background Current single cell analysis methods annotate cell types at cluster-level rather than ideally at single cell level. Multiple exchangeable clustering methods and many tunable parameters have a substantial impact on the clustering outcome, often leading to incorrect cluster ...
Yang, Xiaofei   +5 more
openaire   +2 more sources

Single and fractionated ionizing radiation induce alterations in endothelial connexin expression and channel function [PDF]

open access: yes, 2019
Radiotherapy is an effective treatment for most tumor types. However, emerging evidence indicates an increased risk for atherosclerosis after ionizing radiation exposure, initiated by endothelial cell dysfunction. Interestingly, endothelial cells express
Aerts, An   +8 more
core   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

On the Performance Gain of NOMA over OMA in Uplink Communication Systems

open access: yes, 2019
In this paper, we investigate and reveal the ergodic sum-rate gain (ESG) of non-orthogonal multiple access (NOMA) over orthogonal multiple access (OMA) in uplink cellular communication systems. A base station equipped with a single-antenna, with multiple
Hanzo, Lajos   +4 more
core   +1 more source

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