Results 91 to 100 of about 1,819,963 (351)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Crystal Growth and Spectroscopy of Yb²⁺-Doped CsI Single Crystal

Crystals
The single crystals of CsI-Yb2+ were grown, and their spectroscopic studies were conducted. The observed luminescence in CsI-Yb2+ is due to 5d–4f transitions in Yb2+ ions.
Dmitriy Sofich, Alexandra Myasnikova, Alexander Bogdanov, Viktorija Pankratova, Vladimir Pankratov, Ekaterina Kaneva, Roman Shendrik   +6 more
doaj   +1 more source

Causes analysis on cracks in nickel-based single crystal superalloy fabricated by laser powder deposition additive manufacturing

Materials & Design, 2018
Additive manufacturing is an advanced forming method to fabricate complex components, while cracks appear in the deposited nickel-based single crystal superalloy samples undesirably.
Zhipeng Zhou, Lan Huang, Yijing Shang, Yunping Li, Liang Jiang, Qian Lei   +5 more
doaj   +1 more source

Single Crystal Membranes [PDF]

Single crystal a- and c-axis tubes and ribbons of sodium beta-alumina and sodium magnesium beta-alumina were grown from sodium oxide rich melts. Additional experiments grew ribbon crystals containing sodium magnesium beta, beta double prime, beta triple ...
Morrison, A., Stormont, R. W.
core   +1 more source

Electrical power dissipation in carbon nanotubes on single crystal quartz and amorphous SiO2

, 2011
Heat dissipation in electrically biased semiconducting carbon nanotubes (CNTs) on single crystal quartz and amorphous SiO2 is examined with temperature profiles obtained by spatially resolved Raman spectroscopy.
Liao, Albert, Pop, Eric, Shim, Moonsub, Tsai, Cheng-Lin   +3 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Current situation of research on test methods for elastic modulus and Poisson’s ratio of single crystal superalloys

Journal of Aeronautical Materials, 2019
In view of the anisotropic characteristics of elastic constants of single crystal superalloys and other materials, this paper summarizes two main existing testing methods for measuring elastic moduli and Poisson’s ratio of single crystal superalloys ...
ZHAO Pengtao, YU Huichen, HE Yuhuai
doaj   +1 more source

Intergrowth and thermoelectric properties in the Bi-Ca-Co-O system

, 2007
Single crystals of the Bi-Ca-Co-O system have been grown using the flux method with cooling from 900$\celsius$ and 950$\celsius$, respectively. The single crystals are characterized by transmission electron microscopy and X-ray diffraction.
Funahashi, Funahashi, H. Chen, Klein, Koshibae, Luo, Maignan, Maignan, Maignan, Masset, Mikami, Tanaka, Terasaki, X.G. Luo, X.H. Chen, Y.C. Jing, Yamamoto   +16 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source