Results 41 to 50 of about 192,399 (285)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Ab initio structure determination from X-ray powder diffraction data [PDF]
Many important crystalline solids cannot be prepared in the form of single crystals of sufficient size and quality for single crystal X-ray diffraction studies, and in such cases it is essential that structural information can be extracted from powder ...
Tremayne, Maryjane
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
X-ray diffraction on a single crystal: first Bragg peak [PDF]
Single crystal X-ray diffractometer experiment with lithium fluoride crystal showing the first diffraction peak at the first Bragg angle. From TLP:http://www.msm.cam.ac.uk/doitpoms/tlplib/xray-diffraction/single_crystal.php > X-ray diffraction [...]
DoITPoMS, University of Cambridge
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
X-ray diffraction on a single crystal: second Bragg peak [PDF]
Single crystal X-ray diffractometer experiment with lithium fluoride crystal showing the second diffraction peak at the second Bragg angle.
DoITPoMS, University of Cambridge
core
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Characterisation of very thin epitaxial layers by high resolution x-ray diffraction [PDF]
X-rays can be used as a sensitive, non-destructive probe for the characterisation of semiconductors. The energy and wavelength of X-rays is such that structural information down to the Ảngstrom level can be yielded with a depth penetration of several ...
Miles, S.J, Miles, Simon Jonathon
core
Suppressing Diffraction-Related Intensity Losses in Transmissive Single-Crystal X-ray Optics
The highest-quality X-ray optics can be made of single-crystal materials such as silicon, germanium, or, even better, diamond. Unfortunately, such X-ray optics have one drawback: diffraction losses or the “glitch effect”.
Nataliya Klimova +3 more
doaj +1 more source

