Results 131 to 140 of about 7,977,529 (305)
African Journal of Psychological AssessmentThe Patient Health Questionnaire-9 (PHQ-9) is an effective tool for identifying depressive disorders in diverse populations, making it a valuable resource in both clinical practice and research.
Tyrone B. Pretorius +1 more
doaj +1 more source
Angiosarcoma: clinical outcomes and prognostic factors, a single-center analysis
Journal of Cancer Research and Clinical OncologyAbstract Purpose This study sought to investigate oncological outcomes and prognostic factors for patients with angiosarcomas (AS). Methods This single-center, retrospective cohort study, analyzed histopathologically confirmed AS cases. Primarily diagnosed, locally recurrent
Roohani, Siyer +9 more
openaire +3 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Xibei zhiwu xuebao[Objective] This study aims to explore the relationship between seed morphological and physical characteristics and seed vigor of Abies beshanzuensis, in order to provide a theoretical basis for further population renewal and protection of this ...
LÜ Hongfei +5 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Analysis of Credit Risk and Single / Two Factor Model [PDF]
, 2022 Since 2008, businesses and banks must manage and track more risk than ever before. Financial risk management helps companies and banks decrease the risk of investment and trade. Additionally, financial risk management gives a guide on how to forecast and manage the risk efficiently. More specifically, the three major risks are market risk, credit risk,
openaire
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
A Generalized Knowledge Production Function [PDF]
This paper presents a generalized production model based on the knowledge production function. The model allows the relationships between corporate competitiveness strategy, innovation, efficiency, productivity growth and outsourcing to be investigated ...
Heshmati, Almas
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