Results 231 to 240 of about 7,977,529 (305)

Detector-specific correction factors for small-field photon dosimetry in magnetic resonance-guided radiation therapy: A systematic review and meta-analysis. [PDF]

Med Phys
Bedir ME, Khan AU, Culberson W.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The impact of physical activity on social anxiety among college students: an analysis of the chain mediation effect of family support and self-efficacy. [PDF]

PeerJ
Yang B, Yang X, Fan Z, Liu C, Zheng Z.
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Predictive accuracy of multiple regression analysis stratified into four groups of admission motor FIM based on decision tree analysis. [PDF]

Jpn J Compr Rehabil Sci
Tokunaga M, Sannomiya K.
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Multi-omics dissection of SNP-mediated immunometabolic signatures in Alzheimer's disease reveals a novel individual predictive model. [PDF]

NPJ Digit Med
Wu J, Wang X, Tian Q, Yin C, Gao D, Ai X, Yang X, Xiao T, Gao Y, He F, Ke J, Yao W, Feng X, He D, Yu L, Zhang J, Yu Y, Xiong N, Wang LL.   +18 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Integrative Multiscale Analysis Reveals EFNA1-Driven Immune Remodeling Promotes Colorectal Cancer Lymph Node Metastasis. [PDF]

Hum Mutat
Ning W, Qiao N, Zhou L, Li Z, Zhang L, Song X, Chen S.   +6 more
europepmc   +1 more source

Single-molecule analysis of sigma factor release

, 2016
Kapanidis, A, Margeat, E, Laurence, T, Lee, N, Doose, S, Mukhopadhyay, J, Kortkhonjia, E, Ebright, R, Weiss, S   +8 more
openaire   +1 more source