Results 201 to 210 of about 2,809,841 (250)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Clinical Workload, Demographic Patterns, and Correlations in Neurology Ambulatory Care: A Single-Center Study from Bulgaria. [PDF]

Int J Environ Res Public Health
Naydenov CK, Yordanova AP.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Digital platforms for ethics review: a mini review. [PDF]

Front Digit Health
Odero BA, Groenewald C.
europepmc   +1 more source

Discovery of A <i>SLAMF1</i> Gene Change That Increases Dogs' Risk of Developing Canine Atopic Dermatitis: a Plain Language Summary. [PDF]

Vet Q
Forman OP, Freyer J, Kerr A, Labadie JD, Gow DJ, Alexander J.   +5 more
europepmc   +1 more source

High-Speed Volumetric Dual-Mode Ultrasound and Photoacoustic Tomography With a Single-Element Detector. [PDF]

IEEE Trans Med Imaging
Basumatary J, Aborahama Y, Zhang Y, Zhang Y, Zeng Y, Liu CZ, Zhou Q, Wang LV.   +7 more
europepmc   +1 more source

Health in a Digital Age: From Determinants to Dynamic Systems. [PDF]

Health Data Sci
Williams MA.
europepmc   +1 more source

Perspectives on the US Graduate Medical Education Accreditation System in the Context of the Current Policy Climate. [PDF]

J Grad Med Educ
LaVanture D.
europepmc   +1 more source