Results 151 to 160 of about 23,910,911 (290)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
UAV-Based Multispectral Inversion of Integrated Cotton Growth
AgronomyCotton growth monitoring can provide macroscopic information for cotton field management. In this paper, we utilised UAV multispectral remote sensing to monitor cotton growth and constructed a Comprehensive Growth Index (CGI) by combining cotton multi ...
Haozheng Gu +5 more
doaj +1 more source
A New Bayesian Single Index Model with or without Covariates Missing at Random. [PDF]
Bayesian Anal, 2020 Dhara K, Lipsitz S, Pati D, Sinha D.
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
, 2014 Analisa Perbandingan Kinerja Portfolio Optimal yang Dibentuk Menggunakan Single Index Model dan Multi Index dalam Kondisi Pasar Bullish dan Bearish - single index, multi ...
FEBIANA SASIANG, DEBRA
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
EVALUASI KINERJA PORTOFOLIO ANTARA SAHAM SYARIAH DENGAN SAHAM KONVENSIONAL DI BURSA EFEK INDONESIA
Performance, 2018 Efficient portfolio is achieved by combining several securities with the right proportions that maximize return and minimize risk. Optimal portfolio even advisable formed to know the best one stock alternatives, are next to be done that portfolio ...
Ari Noviastuty
doaj
Forecasting of Passenger Conveyances in Latvian Regions Applying Semiparametric Regression Models
In this paper the regression models used for description and forecasting the rail passenger conveyances of the regions of Latvia are considered. Two estimation approaches were compared: parametric and semi-parametric (single index model).
Santalova, Diāna
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source