Results 91 to 100 of about 906,300 (301)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

THE ELECTRICAL AND PHYSICAL EFFECTS OF YARNS CONTAINING METAL WIRE ON KNITTED FABRIC [PDF]

open access: yesAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2019
The textile industry is developed with the proliferation of technological developments and the functionalization of products about conductive textile structures day by day.
CANOGLU Suat, SUNTER EROGLU Nilsen
doaj  

Leveraging State Economic Development Resources to Create Job Opportunities for People with Disabilities [PDF]

open access: yes, 2009
A 2009 research brief produced for the NTAR Leadership Center, a consortium led by the John H. Heldrich Center for Workforce Development at Rutgers, The State University of New Jersey.
Allison Kopicki   +2 more
core  

Powering of IOTs through single jersey wearable tribo-electric nano generator

open access: yesEngineering Research Express
Abstract A simple, lightweight, and easy to develop Single Jersey Wearable Tribo-Electric Nano Generators (SJ-WTENG) were constructed using Cotton and Acrylic fabrics (Triboelectric series materials). Fabrics were also coated with Maghemite (γ-Fe2O3) nanoparticles (13 nm) to increase the electrical conductance of the samples. Compression
Muhammad Amir   +3 more
openaire   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

A Century Apart: New Measures of Well-Being for U.S. Racial and Ethnic Groups [PDF]

open access: yes, 2010
Our national conversation about race tends to take place in black and white, yet the greatest disparities in human well-being to be found in the U.S. are between Asian Americans in New Jersey and Native Americans in South Dakota.
Kristen Lewis, Sarah Burd-Sharps
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

"A comparative study between Lycra Blending ratios on different fibers and structures of Weft Knitted Fabrics produced for Outer Clothes"

open access: yesJournal of Architecture, Art & Humanistic Science, 2018
In the last years of Twentieth century there have been real changes and rapid developments in all areas of life and modern techniques have emerged in textile industries ranked first position in strategic fields .
Fayrouz El Gamal   +2 more
doaj   +1 more source

Implementing Connections: The Benefits for Greater Philadelphia [PDF]

open access: yes, 2011
This analysis utilizes DVRPC's modeling capabilities to illustrate and quantify the benefits of implementing the policies and goals defined in the Connections Plan, through a Plan scenario, compared to a continuation of our region's business-as-usual ...

core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

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