Results 161 to 170 of about 4,005,529 (300)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Monolithic integration of one VCSEL on a single mode fiber. [PDF]

Nanophotonics
Piccirillo F, Zimmer M, Giaquinto M, Micco A, Jetter M, Michler P, Cusano A, Portalupi SL, Ricciardi A.   +8 more
europepmc   +1 more source

Single-mode quasi PT-symmetric laser with high power emission. [PDF]

Light Sci Appl, 2023
Şeker E, Olyaeefar B, Dadashi K, Şengül S, Teimourpour MH, El-Ganainy R, Demir A.   +6 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

OTDR Development Based on Single-Mode Fiber Fault Detection. [PDF]

Sensors (Basel)
Liu H, Zhao T, Zhang M.
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Single-Mode Emission by Phase-Delayed Coupling Between Nanolasers. [PDF]

ACS Photonics
Raziman TV, Fischer A, Nori R, Chan A, Ng WK, Saxena D, Hess O, Molkens K, Tanghe I, Geiregat P, Van Thourhout D, Barahona M, Sapienza R.   +12 more
europepmc   +1 more source

On-chip generation of single-photon circularly polarized single-mode vortex beams. [PDF]

Sci Adv, 2023
Liu X, Kan Y, Kumar S, Komisar D, Zhao C, Bozhevolnyi SI.   +5 more
europepmc   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Board-level single-mode polymer optical waveguides [PDF]

, 2013
Bosman, Erwin, Elmogi, Ahmed, Guindi, Rafik, Kalathimekkad, Sandeep, Missinne, Jeroen, Teigell Beneitez, Nuria, Van Steenberge, Geert   +6 more
core   +1 more source