Results 211 to 220 of about 10,475,199 (348)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

AFM-Based Single-Molecule Force Spectroscopy of PEG-Anti-PEG Antibody Interactions. [PDF]

ACS Appl Bio Mater
Latag GV, Tahara H, Katase A, Maeda S, Liu Y, Kakuta Y, Teramoto T, Mori T, Hayashi T.   +8 more
europepmc   +1 more source

Multiplex chromatin interactions with single-molecule precision

Nature, 2019
Meizhen Zheng, S. Tian, D. Capurso, Minji Kim, Rahul Maurya, Byoungkoo Lee, Emaly Piecuch, Liang Gong, J. J. Zhu, Zhihui Li, Chee-Hong Wong, C. Ngan, Ping Wang, Xiaoan Ruan, Chia-Lin Wei, Y. Ruan   +15 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Label-Free Single-Molecule Immunoassay. [PDF]

Adv Sci (Weinh)
Zhou X, Chen C, Zhou S, Ma G, Chemerkouh MJHN, Snozek CLH, Yang EH, Jiang J, Braswell B, Wan Z, Zhou X, Wang S.   +11 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Single-shot Stokes polarimetry of plasmon-coupled single-molecule fluorescence. [PDF]

Nanophotonics
Mahajan S, Wang Y, Huijben TAPM, Marie R, Zijlstra P.   +4 more
europepmc   +1 more source

The development of anticancer ruthenium(ii) complexes: from single molecule compounds to nanomaterials.

Chemical Society Reviews, 2017
Leli Zeng, Pranav Gupta, Yanglu Chen, E. Wang, L. Ji, Hui Chao, Zhe-Sheng Chen   +6 more
semanticscholar   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Dual-view microscopy of single-molecule dipole orientations. [PDF]

Biophys Rep (N Y)
Sun Y, Wang Q.
europepmc   +1 more source