Results 111 to 120 of about 308,535 (321)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Lanthanides in the frame of Molecular Magnetism

EPJ Web of Conferences, 2014
Molecular magnetism is producing new types of materials which cover up to date aspects of basic science together with possible applications. This article highlights recent results from the point of view of lanthanides which are now intensively used to ...
Gatteschi D.
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Multifunctional Dy³⁺ Complexes with Triphenylmethanolates: Structural Diversity, Luminescence, and Magnetic Relaxation

Molecules
The coordination environment of magneto-luminescent Dy3+-based Single-Molecule Magnets (SMM) is a crucial factor influencing both magnetic and luminescent properties.
Gautier Félix, Aleksei O. Tolpygin, Aurore Larquey, Ilia A. Gogolev, Yulia V. Nelyubina, Yannick Guari, Joulia Larionova, Alexander A. Trifonov   +7 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Enhancing the Magnetic Behaviors of Dy₂ Complexes by Modulating the Crystal Field Environment with Different μ-O Bridging Ligands

Molecules
Four similar dinuclear lanthanide complexes have been synthesized by linking two [Ln(hfac)2–3] units (hfac stands for hexafluoroacetylacetone) with different μ-O bridging ligands.
Xirong Wang, Min Zhou, Wen Wang, Fangting Zhu, Shijia Qin, Xiulan Li, Feifei Bai, Qinglun Wang, Licun Li, Yue Ma, Bin Zhao   +10 more
doaj   +1 more source

Cyanometallate-Bridged Didysprosium Single-Molecule Magnets Constructed with Single-Ion Magnet Building Block.

Inorganic Chemistry, 2019
The combination of magnetic interaction with high magnetic anisotropy provides a promising way for modulating/fine-tuning molecular magnetic behaviors.
Yang Liu, Yan‐Cong Chen, Jiang Liu, Wen-Bin Chen, Guo‐Zhang Huang, Si-Guo Wu, Jin Wang, Jun‐Liang Liu, M. Tong   +8 more
semanticscholar   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Interaction of spin and vibrations in transport through single-molecule magnets

Beilstein Journal of Nanotechnology, 2011
We study electron transport through a single-molecule magnet (SMM) and the interplay of its anisotropic spin with quantized vibrational distortions of the molecule.
Falk May, Maarten R. Wegewijs, Walter Hofstetter   +2 more
doaj   +1 more source

Million-fold Relaxation Time Enhancement across a Series of Phosphino-Supported Erbium Single-Molecule Magnets.

Journal of the American Chemical Society, 2019
Maintaining strong magnetic anisotropy in the presence of collective spin interactions has become a defining challenge in the advancement of single-molecule magnet (SMM) research. Herein we demonstrate effective decoupling of these often competing design
Jeremy D. Hilgar, Maximilian G. Bernbeck, Jeffrey D. Rinehart   +2 more
semanticscholar   +1 more source