Results 121 to 130 of about 15,624,994 (334)

Microglial TSPAN4‐Dependent Migrasomes Promote Pathological Retinal Neovascularization via Immune‐Vascular Crosstalk

open access: yesAdvanced Science, EarlyView.
Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu   +12 more
wiley   +1 more source

Letter from Mother Fish, Partridge Island, [New York?], to her son, Edmund Fish, Bellevue Hospital, New York, August 21, 1863

open access: yes
A letter sent from Mother Fish to her son Edmund Fish, in Bellevue Hospital.
Fish, Mother
core  

[Blessing from Mother Superior]

open access: yes, 1967
1 leaf ; 1 sided.This letter is blessing from Mother ...
Mother Superior
core  

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

open access: yesAdvanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang   +16 more
wiley   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

open access: yesAdvanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan   +7 more
wiley   +1 more source

COMPARATIVE STUDY OF THE MOTHER SPOROCYST OF SCHISTOSOMA MANSONI IN THE SUSCEPTIBLE AND RESISTANT SNAILS OF BIOMPHALARIA GLABRATA [PDF]

open access: yesPakistan Veterinary Journal, 2007
The comparative studies of the susceptible and resistant snails of Biomphalaria glabrata mass exposed to miracidia of Schistosoma mansoni were conducted from 1 to10 days post-exposure (DPE). Histological sections of 50 susceptible and 50 resistant snails
I. B. KALHORO, S. JALALI1 AND S. A. SHAMI
doaj  

Hierarchical Nanoplatform Integrating Oxidative–Acidic Microenvironment Remodeling and Bone Homeostasis Modulation for Diabetic Bone Defect Therapy

open access: yesAdvanced Science, EarlyView.
A hierarchical CM/LDH nanoplatform integrates ROS‐scavenging Ce‐MOF nanozymes with acid‐neutralizing CaAl‐LDH and is delivered within GelMA hydrogel to diabetic bone defects. By remodeling the oxidative‐acidic microenvironment, preserving mitochondrial homeostasis, and suppressing mtDNA–cGAS–STING inflammatory signaling, CM/LDH reduces proinflammatory ...
Xu Chen   +10 more
wiley   +1 more source

Letter from Mother Fish, Partridge Island, [New York?], to her son, Edmund Fish, Bellevue Hospital, New York, August 10, 1862

open access: yes
A letter written by Edmund Fish's mother from Partridge Island to her son in Bellevue Hospital, New York. She asks if he is stopped smoking now and thought that quitting was related to him having a fit.
Fish, Mother
core  

Solvent‐Free Synthesis of Ultrabright Carbon Dots With Near‐Unity Quantum Yield for High‐Performance Light‐Emitting Diodes

open access: yesAdvanced Science, EarlyView.
A rational, solvent‐free synthesis utilizing 2,6‐diaminonaphthalene produces ultrabright green‐emissive carbon dots. Regulated by a self‐limiting oxidative capping mechanism, excitons undergo ultrafast intra‐particle funneling from the nitrogen‐doped carbon core to emissive surface traps.
Hyeonjin Park   +8 more
wiley   +1 more source

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