Results 271 to 280 of about 1,522,500 (352)

Role of single-nucleotide polymorphism microarray in the classification of BAP1-inactivated melanocytic tumours. [PDF]

Histopathology
Durgin JS, Zoumberos NA, Novice T, Fullen DR, Hristov AC, Lowe L, Patel RM, Harms PW, Andea AA, Bresler SC.   +9 more
europepmc   +1 more source

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

Advanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang, Houyu Ling, Xizong Chen, Yufei Duan, Yu Liu, Shuntian Cai, Yandan Ren, Wenlong Li, Lei Ren, Miao Wang   +9 more
wiley   +1 more source

Genome-Wide Meta-Analysis Identifies Five Single-Nucleotide Polymorphisms Associated With Both Vitiligo and Freckles in the Chinese Han Population. [PDF]

J Cosmet Dermatol
Lu J, Wang Y, Li Z, Yu J, Song C, Wang M, Yan S, Du J, Liu C, Guo X, Feng X, Niu W, Lv M, Chen W, Han Y, Zhen Q, Sun L.   +16 more
europepmc   +1 more source

Nanomaterial‐Based Optical Biosensors for SARS‐CoV‐2 Detection: A Retrospective of the Pandemic

Advanced Sensor Research, EarlyView.
This review discusses nanomaterial‐based optical biosensors developed for or adapted to the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). It concludes by providing a perspective on how lessons learned during the coronavirus disease of 2019 (COVID‐19) pandemic may be applied for future research on nanomaterial‐based ...
Flavie Martin, Scott G. Harroun, Michel Meunier   +2 more
wiley   +1 more source

A <i>POLR1D</i>-regulating single-nucleotide polymorphism as a predictive marker candidate for platinum-based chemotherapy in gastrointestinal cancers. [PDF]

Ther Adv Med Oncol
Mori T, Ueno K, Nagasaki M, Matsuda K, BioBank Japan Project.   +4 more
europepmc   +1 more source

Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility

Advanced Therapeutics, EarlyView.
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam, Lu Yanjun, Bee Luan Khoo, Tongxu Si, Heng Zou, Mengsu Yang   +5 more
wiley   +1 more source

A single-nucleotide variant conditions the ability vs. inability of <i>Propionibacterium freudenreichii</i> to utilize L-lactate. [PDF]

Appl Environ Microbiol
Cocuzzi R, Turgay M, Schmidt RS, von Ah U, Bachmann H-P, Weisskopf L, Fröhlich-Wyder M-T.   +6 more
europepmc   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Enhanced Doxorubicin Cytotoxicity on Breast Cancer Spheroids by Aptamer Targeted Co‐Delivery with Hyaluronidase

Advanced Therapeutics, EarlyView.
Breast cancer is one of the most prevalent solid tumors in women. Doxorubicin is loaded mesoporous silica nanoparticles, capped with HER2‐specific aptamers, and the particle surface is functionalized with hyaluronidase. This dual‐functionalized nanocarrier system offers a promising solution for the drug resistance by solid tumors.
Murat Kavruk, Dide Su Demirel, Farzaneh Bonyadi, Buket Çakmak Güner, Ali Doğan Dursun, Cekdar Vakifahmetoglu, Bilge Güvenç Tuna, Uğur Şahin, Veli Cengiz Ozalp   +8 more
wiley   +1 more source

Genetic Engineering Methods in Primary T Cells

Advanced Therapeutics, EarlyView.
Primary T cells can be engineered to confer them with novel therapeutic functions, allowing them to treat a variety of conditions. Genetic engineering can be either stable or transient, aiming to either express or inhibit a target gene. This review discusses the various genetic engineering tools available as well as their characteristics and ...
Anthony Youssef, Hui‐Shan Li
wiley   +1 more source