Results 31 to 40 of about 1,653,696 (343)

Integrated Human Skin Bacteria Genome Catalog Reveals Extensive Unexplored Habitat‐Specific Microbiome Diversity and Function

Advanced Science, 2023
The skin is the largest organ in the human body. Various skin environments on its surface constitutes a complex ecosystem. One of the characteristics of the skin micro‐ecosystem is low biomass, which greatly limits a comprehensive identification of the ...
Zhiming Li, Yanmei Ju, Jingjing Xia, Zhe Zhang, Hefu Zhen, Xin Tong, Yuzhe Sun, Haorong Lu, Yang Zong, Peishan Chen, Kaiye Cai, Zhen Wang, Huanming Yang, Jiucun Wang, Jian Wang, Yong Hou, Xin Jin, Tao Zhang, Wenwei Zhang, Xun Xu, Liang Xiao, Ruijin Guo, Chao Nie   +22 more
doaj   +1 more source

Polymorphism of SNP g.8398A>G at prolactin gene and its effect on Indonesian Holstein dairy cow’s milk performance and reproductive traits

Journal of the Indonesian Tropical Animal Agriculture, 2023
The objective of this study was to identify the polymorphism of Single Nucleotide Polymorphism (SNP) g.8398A>G at the prolactin gene exon 4 in Indonesian Holstein dairy cows and its effect on milk production, milk quality, and reproductive traits.
Y. W. Setyorini, S. Sutopo, E. Kurnianto, S. Sutiyono   +3 more
doaj   +1 more source

Quantifying single nucleotide variant detection sensitivity in exome sequencing [PDF]

, 2013
BACKGROUND: The targeted capture and sequencing of genomic regions has rapidly demonstrated its utility in genetic studies. Inherent in this technology is considerable heterogeneity of target coverage and this is expected to systematically impact our ...
A McKenna, AJ Coffey, Alison M Meynert, AM Sulonen, Andrew P Jackson, B Lehne, B Timmermann, DN Cooper, E Kalay, H Li, H Li, J Parla, JF Degner, JK Teer, K Fransen, KK Mantripragada, Louise S Bicknell, M Choi, MA Depristo, Martin S Taylor, Matthew E Hurles, MD Mailman, MJ Clark, MN Bainbridge, MW Hahn, R Leinonen, RA Harte, RE Thurman, SB Ng, SB Ng, SB Ng, SS Ajay, The International HapMap 3 Consortium, Y Li, Y Xu   +34 more
core   +2 more sources

The C242T polymorphism of the NAD(P)H oxidase p22(phox) subunit is associated with an enhanced risk for cerebrovascular disease at a young age [PDF]

, 2008
Background and Purpose: Oxidative stress has been proposed as a major contributing factor for vascular disease, that acts independently from its participation in predisposing disorders such as diabetes and arterial hypertension.
Genius, Just, Grau, Armin J., Lichy, Christoph   +2 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Causal associations between both psoriasis and psoriatic arthritis and multiple autoimmune diseases: a bidirectional two-sample Mendelian randomization study

Frontiers in Immunology
BackgroundNumerous observational studies have identified associations between both psoriasis (PsO) and psoriatic arthritis (PsA), and autoimmune diseases (AIDs); however, the causality of these associations remains undetermined.MethodsWe conducted a ...
Kexin Duan, Jingrui Wang, Shaomin Chen, Tong Chen, Jiajue Wang, Shujing Wang, Xinsheng Chen   +6 more
doaj   +1 more source

The genetic architecture of blood pressure variability: A genome‐wide association study of 9370 participants from UK Biobank

The Journal of Clinical Hypertension, 2022
Long‐term blood pressure variability (BPV) is a risk factor for cardiovascular diseases, dementia, and stroke. However, its genetic architecture is not fully understood.
Pingping Jia, Na Zhan, Baker K. K. Bat, Qi Feng, Kelvin K. F. Tsoi   +4 more
doaj   +1 more source

A Novel Single Nucleotide Polymorphism in Exon 4 of Insulin-Like Growth Factor-1 Associated with Production Traits in Bali Cattle [PDF]

, 2012
Insulin-like growth factor-1 (IGF-1) is one of the gene candidates that can be used in selection strategy by using DNA markers (marker assisted selection).
Arman, C. (C), Gurnadi, E. (E), Maskur, M. (Maskur), Muladno, M. (Muladno), Sumantri, C. (C)   +4 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Identification of Single Nucleotide Polymorphisms on Cattle Breeds in Indonesia Using Bovine 50k [PDF]

, 2015
Single nucleotide polymorphisms (SNPs) abundant in bovine genome influence genetic variation in biological mechanism. The study aimed to identify SNPs on Indonesian cattle breeds and analyze their genetic diversity using Bovine 50K SNP chip. Twenty eight
Anggraeni, A. (Anneke), Lestari, P. (Puji), Lutfi, M. (Muchamad), Rijzaani, H. (Habib), Rosdianti, I. (Ida), Satyawan, D. (Dani), Tasma, I. M. (I), Utami, D. W. (Dwinita)   +7 more
core