Results 101 to 110 of about 167 (165)

Rapid Diagnostic Testing for Infective Endocarditis and Myocarditis Using Nanopore Targeted Sequencing

iLABMED, EarlyView.
This research presents a method based on nanopore targeted sequencing (NTS) with pathogen‐specific panels for testing infective endocarditis (IE) and myocarditis. The NTS achieved a detection limit of 20 copies/test for the IE target panel and 10 copies/test for the myocarditis target panel.
Aisi Fu, Xian Wang, Zhiyong Shen, Jiashuang Gu, Ting Zhang, Feiyan Wang, Shiyu Jia, Linmei Yang, Feng Li, Jie Geng, Jun Cheng   +10 more
wiley   +1 more source

A novel genotyping system based on site polymorphism on spike gene reveals the evolutionary pathway of porcine epidemic diarrhea virus

iMetaOmics, EarlyView.
This study focuses on porcine epidemic diarrhea virus (PEDV), a highly virulent and rapidly evolving coronavirus threatening global swine production. We established a novel genotype system of PEDV targeting site‐specific polymorphisms in the spike (S) protein.
Mingkai Lei, Huimin Li, Xiaoyu Chen, Xiaozhen Li, Xuexiang Yu, Shengnan Ruan, Hao Wu, Ahmed H. Ghonaim, Ziyang Yan, Wentao Li, Qigai He   +10 more
wiley   +1 more source

single nucleotide polymorphism(SNP)

Journal of JCS Cardiologists, 2002
openaire   +3 more sources

Haplotype‐resolved genome and pan‐genome graphs reveal the impacts of structural variation on functional genome and feather colors in chickens

iMetaOmics, EarlyView.
This study built a Wenchang chicken haplotype genome and integrated it with 29 others to create a chicken pangenome atlas. Analysis of 354 chickens revealed 185,205 structural variations (SVs), with one‐third derived from homology‐based and transposable elements.
Lihong Gu, Chen Peng, Anhong Chen, Kaiyu Chen, Xinli Zheng, Dongyou Yu, Zhengguang Wang, Lingzhao Fang, George E. Liu, Pengju Zhao   +9 more
wiley   +1 more source

Soyasaponin and vertical microbial transmission: Maternal effect on the intestinal development and health of early chicks

iMeta, EarlyView.
This study investigates the vertical transmission of maternal microbiota in chickens and how it is modulated by maternal soyasaponin supplementation. Using a model spanning the reproductive tract, egg components, and developing chicks, we show that maternal gut and reproductive microbiota, including Bifidobacterium adolescentis (B.
Mingkun Gao, Shu Chen, Hao Fan, Peng Li, Aiqiao Liu, Dongli Li, Xiaomin Li, Yongfei Hu, Guofeng Han, Yuming Guo, Zengpeng Lv   +10 more
wiley   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

A Simple and Fast Optical Clearing Method for Whole‐Mount Fluorescence In Situ Hybridization (FISH) Imaging

Journal of Biophotonics, EarlyView.
In this article, we present 3D‐LIMPID‐FISH: a simple and fast optical clearing method for acquiring 3D images of fluorescence in situ hybridization probes. Figures and movies are provided to showcase the technology, and a detailed protocol is provided to replicate the result.
Junwoo Suh, Yehe Liu, Jordan Smith, Michiko Watanabe, Andrew M. Rollins, Michael W. Jenkins   +5 more
wiley   +1 more source

A Preliminary Association Study of H19 Non‐Coding Gene Variants With Risk of Non‐Hodgkin Lymphoma: A Case–Control Study and Computational Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
Non‐Hodgkin lymphoma (NHL) is a kind of frequently occurring malignant tumor of the lymphoid hematopoietic system in the world. NHL comprises a large group of diverse lymphoid malignancies involving either the lymph nodes or extra nodal sites. It is more prevalent in males living in more developed countries over the age of 60 years.
Sara Kashani, Hoseinali Sasan, Behrouz Mollashahi, Gholamreza Bahari, Seyed Mahdi Hashemi, Mohsen Taheri   +5 more
wiley   +1 more source

Development and Validation of In‐House Conventional and Multiplex PCR Methods for the Detection and Identification of Lophomonas spp.: An Innovative Approach

Journal of Clinical Laboratory Analysis, EarlyView.
Sequence alignment of the SSU rRNA of the two Lophomonas species, L. blattarum and L. striata. The red rectangle highlights the position of the reverse universal primer; the yellow, the L. blattarum‐specific forward primer; and the green, the L. striata‐specific forward primer used in multiplex PCR.
Maryam Nakhaei, Mahdi Fakhar, Abouzar Bagheri, Hajar Ziaei Hezarjaribi, Saied Abediankenari, Ali Sharifpour, Maryam Ghasemi   +6 more
wiley   +1 more source

In Vitro and Clinical Evaluations of UGT1A1‐, P‐gp‐, OATP1B1‐, and BCRP‐Mediated Drug–Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor

The Journal of Clinical Pharmacology, EarlyView.
Abstract Belumosudil is an oral selective rho‐associated coiled‐coil containing protein kinase 2 inhibitor, approved as a treatment for chronic graft‐versus‐host disease. Prior clinical studies demonstrated that coadministration with strong CYP3A4 inducers or proton pump inhibitors requires dose modification of belumosudil.
Olivier Schueller, Lauren Lohmer, Felix Beck, Jeegar Patel, Jasminder Sahi   +4 more
wiley   +1 more source