Results 11 to 20 of about 263,691 (312)
Detection of Single-Nucleotide Polymorphism
BioTechniques, 1998 Weikuan Gu +2 more
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Electrophoretic Detection of Single-Nucleotide Polymorphisms [PDF]
BioTechniques, 2000 Single-nucleotide polymorphisms (SNPs) represent the most prevalent class of genetic markers available for linkage disequilibrium or cladistic analyses. PCR primers may be labeled with fluorescent dyes and used to rapidly and accurately differentiate among alleles that are defined by a single-nucleotide differences.
Deven R. See +3 more
openalex +5 more sources
Genetic epidemiology of single-nucleotide polymorphisms [PDF]
Proceedings of the National Academy of Sciences, 1999 On the causal hypothesis, most genetic determinants of disease are single-nucleotide polymorphisms (SNPs) that are likely to be selected as markers for positional cloning. On the proximity hypothesis, most disease determinants will not be included among markers but may be detected through linkage disequilibrium with other SNPs.
Andrew Collins +2 more
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Single-Nucleotide Polymorphisms in Soybean [PDF]
Genetics, 2003 Abstract Single-nucleotide polymorphisms (SNPs) provide an abundant source of DNA polymorphisms in a number of eukaryotic species. Information on the frequency, nature, and distribution of SNPs in plant genomes is limited. Thus, our objectives were (1) to determine SNP frequency in coding and noncoding soybean (Glycine max L.
Perry B. Cregan +12 more
openaire +3 more sources
Detection of Single Nucleotide Polymorphisms [PDF]
Current Issues in Molecular Biology, 2003 Single nucleotide polymorphism (SNP) detection technologies are used to scan for new polymorphisms and to determine the allele(s) of a known polymorphism in target sequences. SNP detection technologies have evolved from labor intensive, time consuming, and expensive processes to some of the most highly automated, efficient, and relatively inexpensive ...
Kwok, Pui-Yan, Chen, Xiangning
openaire +3 more sources
Association of Single Nucleotide Polymorphisms in the PYGO2 and PRDM9 Genes with Idiopathic Azoospermia in Iranian Infertile Male Patients [PDF]
Iranian Journal of Medical Sciences, 2023 Background: Azoospermia is a risk factor for infertility affecting approximately 1% of the male population. Genetic factors are associated with non-obstructive azoospermia (NOA). Pygo2 and PRDM9 genes are involved in the spermatogenesis process.
Sanaz Soleymani Moud +3 more
doaj +1 more source
Single Nucleotide Polymorphism Clustering in Systemic Autoimmune Diseases. [PDF]
PLoS ONE, 2016 Systemic Autoimmune Diseases, a group of chronic inflammatory conditions, have variable symptoms and difficult diagnosis. In order to reclassify them based on genetic markers rather than clinical criteria, we performed clustering of Single Nucleotide ...
Thomas Charlon +8 more
doaj +1 more source
Picking single-nucleotide polymorphisms in forests [PDF]
BMC Proceedings, 2007 Abstract With the development of high-throughput single-nucleotide polymorphism (SNP) technologies, the vast number of SNPs in smaller samples poses a challenge to the application of classical statistical procedures. A possible solution is to use a two-stage approach for case-control data in which, in the first stage, a screening test selects
Silke Szymczak +3 more
openaire +3 more sources
p53 codon 72 polymorphism in Taiwanese breast cancer patients
Kaohsiung Journal of Medical Sciences, 2013 There are clear discrepancies between ethnicity and geographic area regarding the peak age incidence and mortality of breast cancer. Underlying variances include genetic, environmental, and socioeconomic factors.
Fang-Ming Chen +4 more
doaj +1 more source
Balkan Medical Journal, 2017 Background: Atopic dermatitis is the most common chronic inflammatory skin disease. A complex interaction of both genetic and environmental factors is thought to contribute to the disease. Aims: To evaluate whether single nucleotide polymorphisms in the
Ceren Can +5 more
doaj +1 more source