Results 271 to 280 of about 479,118 (340)

The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges

Advanced Genetics, EarlyView.
This article examines how the respiratory virome contributes to health and disease, highlighting its interactions with the host and bacteriome. Key disease associations and present knowledge gaps are outlined. The review discusses challenges in sample collection and preprocessing, and presents future research directions for understanding virome ...
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
wiley   +1 more source

A single nucleotide polymorphism produces different transcription profiles in <i>Campylobacter jejuni's cysM</i>. [PDF]

Front Microbiol
Gunther NW, Kanrar S, Abdul-Wakeel A, McAnulty MJ, Renye J, Uknalis J, Uhlich GA.   +6 more
europepmc   +1 more source

Rare Structural Variants Uncovered by Optical Genome Mapping in Multisystem Inflammatory Syndrome in Children (MIS‐C)

Advanced Genetics, EarlyView.
This study applies optical genome mapping (OGM) to children with multisystem inflammatory syndrome (MIS‐C), revealing rare structural and copy number variants in and near immune‐related genes, including ORAI1, STAT4, ITPR1, BATF, CFHR5, and DOCK2.
Catherine A. Brownstein, Caspar I. van der Made, Kristin Cabral, Shira Rockowitz, Donghun Kang, Maximilian Schieck, Andy Wing Chun Pang, Jeffrey M. Robinson, Alex R. Hastie, Alka Chaubey, The C.O.V.I.D19hostgenomeS.V. Consortium, Alexander Hoischen, Alan H. Beggs, Clement A. Adebamowo, Ali Andalibi, Silviu‐Alin Bacanu, Vineet Bafna, Justin Bahl, Hayk Barseghyan, Alan Beggs, Laurie Burdette, Manish Butte, Pantelis Constantoulakis, Keith A. Crandall, Siavash R. Dehkordi, Megan Dennis, Gang Fang, Olivier Fedrigo, Darren Finlay, Michael A. Goldman, Umamaheswaran Gurusamy, Vanessa Hayes, Glenn Hickey, Alexander Hoischen, Thomas Illig, Alexander Ioannidis, Erich Jarvis, Naoru Koizumi, Ravindra Kolhe, Meriem Laamarti, Celia Labranche, Sandra Leibel, Brynn Levy, Matthew Loose, Claudio Mello, Jamal Nasir, Thuy L. Phung, Chethan P. Venkatasubba Rao, Ted Ross, Nikhil S. Sahajpal, Rashmi K. Shamanna, Daniela C. Soto, Amir Trablesi, Zi‐Xuan Wang, Sion Llewelyn Williams, Victoria Wright, Hua Zhao, Michael Zody   +57 more
wiley   +1 more source

CYP2B6*6 single nucleotide polymorphism among patients with uncomplicated malaria in Adjumani district, Uganda: Implications on efficacy of artemether-lumefantrine. [PDF]

PLoS One
Angwe MK, Mwebaza N, Nsobya SL, Kiguba R, Vudriko P, Dralabu S, Omali D, Tumwebaze MA, Ocan M.   +8 more
europepmc   +1 more source

Advances in Detecting RNA Modifications Using Direct RNA Nanopore Sequencing

Advanced Genetics, EarlyView.
This review examines recent advances in Oxford Nanopore Technologies direct RNA sequencing, highlighting its expanding capacity to detect RNA modifications beyond m6A. It discusses computational frameworks and basecalling innovations that enable single‐nucleotide and single‐molecule resolution, explores co‐occurring modifications and their regulatory ...
Yaran Liu, Yang Li, Qiang Sun
wiley   +1 more source

Core-genome Single-nucleotide Polymorphism Analysis of <i>Streptococcus pyogenes</i> M1 Clone from Korea During the Pre-COVID-19 Era. [PDF]

Ann Lab Med
Takahashi T, Maeda T, Shin H, Kim S.
europepmc   +1 more source

Lack of association between the C677T single nucleotide polymorphism of the MTHFR gene and glaucoma in Iranian patients.

, 2012
N Nilforoushan, Sevil Aghapour, Reza Raoofian, Samira Saee Rad, Wayne K. Greene, Ghasem Fakhraie, Mansour Heidari   +6 more
openalex   +1 more source

A novel missense single-nucleotide polymorphism (c.149G>A) in the bovine <i>leptin</i> gene and its association with growth traits in Madura cattle. [PDF]

Vet World
Kuswati K, Novianti I, Prafitri R, Septian WA, Putri RF, Nugraha CD, Furqon A.   +6 more
europepmc   +1 more source

An Integrative Analysis of O6-Methylguanine-DNA Methyltransferase (MGMT) Methylation and the Single-Nucleotide Polymorphism (SNP) rs1625649 Reveals Distinct Survival Patterns in Glioblastoma: A Retrospective Study. [PDF]

Cureus
Agarwal K, Raghuvanshi S, Bhalla S, Raghuvanshi S, Singh A, Singh A, Ojha BK.   +6 more
europepmc   +1 more source

Risk of cervical squamous cell carcinoma associated with a single nucleotide polymorphism in the RAD18 gene in the Chinese population and its significance as a predictive biomarker. [PDF]

Medicine (Baltimore)
Zhang R, Kong J, Li Y, Wang H, Cheng Q, Zhou C, Yu M, Wang Y, Ye F.   +8 more
europepmc   +1 more source