Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu+9 more
wiley +1 more source
Whole genome uniparental isodisomy detected using single nucleotide polymorphism (SNP) microarray in molar pregnancy: a case report. [PDF]
Okonkwo OO+6 more
europepmc +1 more source
Aortic stenosis intricacies beyond the valve: A bidirectional Mendelian randomization study
Abstract Aims Numerous observational studies have reported an association between calcific aortic valve stenosis (CAVS) and an increased risk of other cardiovascular diseases (CVDs). However, the potential causal association is uncertain. Methods and results A bidirectional Mendelian randomization (MR) analysis was performed to confirm the causal ...
Dihui Cai, Jianhui Liu
wiley +1 more source
Genetic diversity and population structure analyses of tropical maize inbred lines using Single Nucleotide Polymorphism markers. [PDF]
Gunundu R, Shimelis H, Tesfamariam SA.
europepmc +1 more source
Summary of the study design and key findings. The (+) and (−) signs mean that the variable has a positive or a negative association with growth differentiation factor‐15 (GDF‐15) levels in the fully adjusted model (age, gender, current smoker, body mass index, total cholesterol, systolic blood pressure and N‐terminal pro‐B‐type natriuretic peptide ...
Luca Monzo+11 more
wiley +1 more source
The <i>RELN</i> heterozygous single-nucleotide polymorphism rs362691 increases the prefrontal cortical thickness and modulates systemizing-related autistic tendencies in typically developing children and adolescents. [PDF]
Sato H+6 more
europepmc +1 more source
Electrochemical sensing strategies for on‐site testing of pathogenic nucleic acids
Abstract Rapid and reliable on‐site pathogen testing is crucial for diagnosing and managing human health. Nucleic acids (NAs) containing genetic information are valuable target molecules for pathogen testing, and sensitive and rapid detection of NAs using electrochemical approaches has been intensively investigated.
Yusuke Kanno+4 more
wiley +1 more source
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons+17 more
wiley +1 more source
Genetic diversity and population structure analysis of 418 tomato cultivars based on single nucleotide polymorphism markers. [PDF]
Xu W, Gong C, Mai P, Li Z, Sun B, Li T.
europepmc +1 more source