Results 351 to 360 of about 708,932 (401)
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Hypertension and single nucleotide polymorphisms
Current Hypertension Reports, 2000Hypertension is a common, complex disease phenotype that has been intensively studied to identify susceptibility loci in humans. Candidate genes continue to be uncovered via genetic analysis in model organisms through linkage analysis with families and/or sib-pairs and through association studies using sequence variants in genes that play a role in key
Deborah A. Nickerson, Mark J. Rieder
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Classifying single nucleotide polymorphisms in humans
Molecular Genetics and Genomics, 2021Single nucleotide polymorphisms (SNPs) are the most common form of genetic variation amongst the human population and are key to personalized medicine. New tests are presented to distinguish pathogenic/malign (i.e., likely to contribute to or cause a disease) from nonpathogenic/benign SNPs, regardless of whether they occur in coding (exon) or noncoding
Shima Azizzadeh-Roodpish +2 more
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ACS Nano, 2012
Graphene materials are being widely used in electrochemistry due to their versatility and excellent properties as platforms for biosensing. However, no records show the use of inherent redox properties of graphene oxide as a label for detection. Here for
A. Bonanni +4 more
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Graphene materials are being widely used in electrochemistry due to their versatility and excellent properties as platforms for biosensing. However, no records show the use of inherent redox properties of graphene oxide as a label for detection. Here for
A. Bonanni +4 more
semanticscholar +1 more source
Single Nucleotide Polymorphisms and Their Applications
2007SNPs are highly abundant in the human genome, explaining most of sequence variation. This makes them a valuable resource for population genetics, evolution, and gene mapping. In this article we have given an overview of the major issues arising in their application to haplotype and haplotype block estimation and genetic association.
Zhaoxia Yu, Rudy Guerra
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Single nucleotide polymorphisms: aging and diseases
Biogerontology, 2004Differences of more than 3 million nucleotides can bee seen comparing the genomes of two individuals as a result of single nucleotide polymorphism (SNP). More and more SNPs can be identified and it seems that these alterations are behind of several biological phenomena.
Margit Zeher +4 more
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ACS Nano, 2011
This paper demonstrated for the first time a simple wet-chemical strategy for synthesizing hemin-graphene hybrid nanosheets (H-GNs) through the π-π interactions.
Yujing Guo +5 more
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This paper demonstrated for the first time a simple wet-chemical strategy for synthesizing hemin-graphene hybrid nanosheets (H-GNs) through the π-π interactions.
Yujing Guo +5 more
semanticscholar +1 more source
Shares in single nucleotide polymorphisms
Expert Opinion on Therapeutic Patents, 1999The announcement of a consortium between the public and private sectors to produce a public single nucleotide polymorphism (SNP) map of the human genome is a unique development which acknowledges the need for research tools to be widely available. The human genome project has been characterised by public-private tensions over information access and ...
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Single Nucleotide Polymorphism Typing
2019Single nucleotide polymorphism (SNP) typing process utilizes biochemical techniques to determine the sequential order of nucleotide bases in a DNA strand using sequencing machines. Last decade has witnessed a tremendous expansion since the invention of the Sanger sequencing.
Srinivasan, Srilakshmi, Batra, Jyotsna
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Methods for Genotyping Single Nucleotide Polymorphisms
Annual Review of Genomics and Human Genetics, 2001One of the fruits of the Human Genome Project is the discovery of millions of DNA sequence variants in the human genome. The majority of these variants are single nucleotide polymorphisms (SNPs). A dense set of SNP markers opens up the possibility of studying the genetic basis of complex diseases by population approaches.
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‘Other’ applications of single nucleotide polymorphisms
Trends in Biotechnology, 2007Single nucleotide polymorphisms (SNPs) are the most frequent form of sequence variation in the human genome, occurring on average every 300 base pairs. Owing to their high density, SNPs are considered useful for identifying the genes associated with complex diseases. The focus of this Opinion article is the recent applications of SNPs that fall outside
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