Results 41 to 50 of about 474,702 (256)

Recent and Ancient Signature of Balancing Selection around the S-Locus in Arabidopsis halleri and A. lyrata [PDF]

, 2012
Balancing selection can maintain different alleles over long evolutionary times. Beyond this direct effect on the molecular targets of selection, balancing selection is also expected to increase neutral polymorphism in linked genome regions, in inverse ...
Castric, Vincent, Charlesworth, Deborah, Pauwels, Maxime, Roux, Camille, Ruggiero, Maria-Valeria, Vekemans, Xavier   +5 more
core   +3 more sources

Functional single nucleotide polymorphism-based association studies

Human Genomics, 2006
Association studies hold great promise for the elucidation of the genetic basis of diseases. Studies based on functional single nucleotide polymorphisms (SNPs) or on linkage disequilibrium (LD) represent two main types of designs.
Carlton Victoria EH, Ireland James S, Useche Francisco, Faham Malek   +3 more
doaj   +1 more source

Development of a molecular method for the rapid screening and identification of the three functionally relevant polymorphisms in the human TAS2R38 receptor gene in studies of sensitivity to the bitter taste of PROP [PDF]

, 2015
The objective of this work was to develop a rapid screening method to identify the three single nucleotide polymorphisms (SNPs) in the TAS2R38 gene, with the aim of providing a significant contribution to studies designed to assess sensitivity to the ...
Atzori, E, Orrù, R, Padiglia, A
core   +2 more sources

Single nucleotide polymorphism (SNP) discovery in polyploid plants

浙江大学学报. 农业与生命科学版, 2011
Single nucleotide polymorphism (SNP) is a kind of DNA polymorphism in genome which results from the variance of single nucleotide. In diploid organisms (such as human, Arabidopsis thaliana, Oryza sativa, etc.), many SNP markers were discovered as genetic
HE Dao-hua, XING Hong-yi, ZHAO Jun-xing, ZHAO Yan-ning, QI Cheng, WANG Yan-ting   +5 more
doaj   +1 more source

Single Nucleotide Polymorphism Promoter -765g/C Gen Cox-2 sebagai Faktor Risiko Terjadinya Karsinoma Kolorektal [PDF]

, 2017
Karsinoma kolorektal (KKR) merupakan keganasan yang berasal dari transformasi neoplastik sel-sel epitel kolon dan rektum, menempati urutan ketiga terbanyak dari seluruh kanker di seluruh dunia.Berbagai Perubahan DNA dapat terjadi akibat paparan dengan ...
Saleh, I. (Irsan), Triwani, T. (Triwani)
core  

Genome resequencing reveals multiscale geographic structure and extensive linkage disequilibrium in the forest tree Populus trichocarpa [PDF]

, 2009
This is the publisher’s final pdf. The article is copyrighted by the New Phytologist Trust and published by John Wiley & Sons, Inc. It can be found at: http://onlinelibrary.wiley.com/journal/10.1111/%28ISSN%291469-8137.
Slavov, Gancho Trifonu, Difazio, Stephen P., Martin, Joel, Schackwitz, Wendy, Muchero, Wellington, Rodgers-Melnick, Eli, Lipphardt, Mindie F., Pennacchio, Christa P., Hellsten, Uffe, Pennacchio, Len A., Gunter, Lee E., Ranjan, Priya, Vining, Kelly, Pomraning, Kyle R., Wilhelm, Larry J., Pellegrini, Matteo, Mockler, Todd C., Freitag, Michael, Geraldes, Armando, El-Kassaby, Yousry A., Mansfield, Shawn D., Cronk, Quentin C. B., Douglas, Carl J., Strauss, Steven H., Rokhsar, Dan, Tuskan, Gerald A.   +25 more
core   +4 more sources

XRCC2 R188H (rs3218536), XRCC3 T241M (rs861539) and R243H (rs77381814) single nucleotide polymorphisms in cervical cancer risk [PDF]

, 2013
Human Papillomavirus (HPV) is the main cause of cervical cancer and its precursor lesions. Transformation may be induced by several mechanisms, including oncogene activation and genome instability.
A Roszak, A Söderlund-Strand, A Udumudi, Andrea Crivaro, B Kuschel, Carlos Daniel Golijow, CL Pearce, EI Cortés-Gutiérrez, G Barbisan, Gisela Barbisan, H Romanowicz-Makowska, J Han, J Huang, J Thacker, K Ruyck De, L Jiao, Lucia Poleri, Luis Orlando Pérez, M Evander, M Kadaja, M Kadaja, M Kadaja, M Kadaja, MA Loizidou, P Magnusson, P Vineis, S Duensing, S Rafii, S Rafii, SA Miller, SS Wang, TC Wright, W Settheetham-Ishida, X He, Y Ting   +34 more
core   +2 more sources

Association between Single Nucleotide Polymorphisms and Endometriosis in a Brazilian Population [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2020
Objective To investigate the association between genetic polymorphisms in candidate genes or candidate regions and the development of endometriosis in Brazilian women.
Paula Coelho Silva Viana, Ana Carolina Delgado Malvaccini Mendes, Lucas Farah Delgado, Gustavo Tostes, Lidiane Gonçalves, Homero Gonçalves Júnior, Nádia Rezende Barbosa Raposo, Geraldo Sérgio Farinazzo Vitral, Pamela Souza Almeida Silva Gerheim   +8 more
doaj   +1 more source

A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity [PDF]

, 2007
Rheumatoid arthritis (RA) is a chronic inflammatory disease with a heritability of 60%. Genetic contributions to RA are made by multiple genes, but only a few gene associations have yet been confirmed.
Alfredsson, L, Burkhardt, H, Holmdahl, Rikard,, Kallberg, H, Klareskog, L, Lindqvist, Anna-Karin,, Lund University., Olsson, Lina,, Padyukov, L   +8 more
core   +2 more sources

Correlation between MDM2 T309G single nucleotide polymorphism and esophageal cancer susceptibility: An updated meta‐analysis

Thoracic Cancer, 2020
Background The aim of this study was to investigate the correlation between MDM2 T309G single nucleotide polymorphism (SNP) and esophageal cancer susceptibility through pooling the open published data.
Lele Yin, Guo Shen, Bin Zhu
doaj   +1 more source