Results 71 to 80 of about 497,054 (287)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Correlation Pyramid Network for 3D Single Object Tracking
3D LiDAR-based single object tracking (SOT) has gained increasing attention as it plays a crucial role in 3D applications such as autonomous driving. The central problem is how to learn a target-aware representation from the sparse and incomplete point clouds.
Wang, Mengmeng +4 more
openaire +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
4D spatio-temporal convolutional networks for object position estimation in OCT volumes
Tracking and localizing objects is a central problem in computer-assisted surgery. Optical coherence tomography (OCT) can be employed as an optical tracking system, due to its high spatial and temporal resolution.
Bengs Marcel +2 more
doaj +1 more source
PPE: Point position embedding for single object tracking in point clouds
Existing 3D single object tracking methods primarily extract features from the global coordinates of point clouds, overlooking the potential exploitation of their positional information.
Yuanzhi Su +3 more
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Real-Time Visual Tracking through Fusion Features
Due to their high-speed, correlation filters for object tracking have begun to receive increasing attention. Traditional object trackers based on correlation filters typically use a single type of feature.
Yang Ruan, Zhenzhong Wei
doaj +1 more source
Due to complex background and volatile object shape-appearance in image, the stability and accuracy of tracking algorithm is often disturbed and reduced.
Xiuyan Tian, Haifang Li, Hongxia Deng
doaj +1 more source
MobiFace: A Novel Dataset for Mobile Face Tracking in the Wild
Face tracking serves as the crucial initial step in mobile applications trying to analyse target faces over time in mobile settings. However, this problem has received little attention, mainly due to the scarcity of dedicated face tracking benchmarks. In
Cheng, Shiyang +3 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source

