Results 161 to 170 of about 6,315,325 (309)

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong   +10 more
wiley   +1 more source

A Comparative Study on the Leisure Participation and Leisure Constraint of Single-Parent Family and Generally Family Household.

open access: yes, 2009
[[abstract]]1. Regular families? favorite leisure activities are reading the newspaper, listening to music, reading books and taking a walk respectively. The least favorite leisure activity was dancing. 2.
HSIEH SU-MI
core  

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Les Fraser

open access: yes, 1998
Interview with Les Fraser, formerly of Trout Lake and Beaton, conducted by Milton Parent at the Ruckle home in Ruckle Provincial Park, Salt Spring Island, British Columbia, May 1998.

core  

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato   +7 more
wiley   +1 more source

Lotus Ruckle

open access: yes, 1998
Interview with Lotus Ruckle (nee Fraser, 2 February 1911-27 October 2010), formerly of Trout Lake and Beaton, conducted by Milton Parent at the Ruckle home in Ruckle Provincial Park, Salt Spring Island, British Columbia, May 1998.

core  

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