Results 51 to 60 of about 10,468,963 (283)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Parents' parenting styles with perfection in single-parent families and several children [PDF]
Scientific Journal of Nursing, Midwifery and Paramedical Faculty, 2017 Background & Aim: It is an effective way to nurture healthy people in the family education community and to provide parents with information. The aim of this study was to investigate the relationship between parental parenting styles and perfectionism in nursing and medical students of the Faculty of Medical Sciences of Abadan and its comparison ...
Nourolah Taheri +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
SPECIFICITY OF CHILDREN'S SOCIALIZATION IN COMPLETE AND PARENT FAMILIES
Соціально-економічні відносини в цифровому суспільствіThe article describes the specifics of the socialization process of children in complete and incomplete families. The research is based on the use of various methods: parental surveys and psychological tests.
Mariia Blikhar, Iryna Subashkevych
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Genre & Histoire, 2016 In 1963, activists of a French pro-family union created the first Committees for women heads of household, which gathered together widows, divorcees and single mothers.
Fiona Friedli
doaj +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Single-parent families and in-work poverty [PDF]
, 2018 Single-parent families face unique challenges when it comes to in-work poverty. Without a second caregiver and earner, single parents have to compete with dual-earner couples for their position in ...
Nieuwenhuis, Rense, Maldonado, Laurie C.
openaire +2 more sources
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
, 1976 Interview with members of the Parent/Leveque family, including Della Parent (nee Leveque, 1903-1998) of Nakusp and son Len Parent (1927-2017) of Delta, formerly of Nakusp, conducted by Milton Parent ...
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