The crystal structure of Pneumolysin at 2.0 Å resolution reveals the molecular packing of the pre-pore complex [PDF]
, 2015 Pneumolysin is a cholesterol-dependent cytolysin (CDC) and virulence factor of Streptococcus pneumoniae. It kills cells by forming pores assembled from oligomeric rings in cholesterol-containing membranes.
Andrew, Peter W +8 more
core +1 more source
Combined shear/compression structural testing of asymmetric sandwich structures [PDF]
, 2004 Asymmetric sandwich technology can be applied in the design of lightweight, non-pressurized aeronautical structures such as those of helicopters. A test rig of asymmetric sandwich structures subjected to compression/shear loads was designed, validated ...
B. Castanié +11 more
core +1 more source
The Layer 0 Inner Silicon Detector of the D0 Experiment
, 2009 This paper describes the design, fabrication, installation and performance of the new inner layer called Layer 0 (L0) that was inserted in the existing Run IIa Silicon Micro-Strip Tracker (SMT) of the D0 experiment at the Fermilab Tevatron collider.
A. Bean +54 more
core +1 more source
Towards comprehensive characterisation and modelling of the forming and wrinkling mechanics of engineering fabrics [PDF]
, 2018 Through a combination of direct measurement and inverse modelling, a route to characterising the main mechanical forming properties of engineering fabric is demonstrated.
Alvarez, Marcos Fernandez +2 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda +15 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
A finite element model capable of predicting resin pockets for arbitrary inclusions in composite laminates [PDF]
, 2012 This work presents the progress in the development of a finite element model capable of predicting resin pockets occurring in composite structures with embedded sensors.
Degrieck, Joris +3 more
core
Delamination resistant composites by interleaving bio-based long-chain polyamide nanofibers through optimal control of fiber diameter and fiber morphology [PDF]
, 2020 In this work an innovative electrospinning system is proposed that simultaneously has an adequate temperature resistance, a high increase in mode I (þ51%) and mode II (þ96%) delamination performance and can be commercially produced.
Daelemans, Lode +5 more
core +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source