Results 51 to 60 of about 16,733 (288)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Revisiting Formability and Failure of AISI304 Sheets in SPIF: Experimental Approach and Numerical Validation

Metals, 2017
Single Point Incremental Forming (SPIF) is a flexible and economic manufacturing process with a strong potential for manufacturing small and medium batches of highly customized parts.
Gabriel Centeno, Andrés Jesús Martínez-Donaire, Isabel Bagudanch, Domingo Morales-Palma, María Luisa Garcia-Romeu, Carpóforo Vallellano   +5 more
doaj   +1 more source

Tool Dynamics During Single Point Incremental Forming Process

, 2014
The single point incremental forming manufacturing process has become increasingly used because of its flexibility in manufacturing single pieces. There exist in the literature many research works that focus on studying the different phenomena observed ...
Martínez-Romero, Oscar, García-Romeu, María Luisa, Bagudanch, Isabel, Elías-Zúñiga, Alex, Olvera-Trejo, Daniel   +4 more
core   +2 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Preliminary studies on single point incremental forming for composite materials

, 2010
This paper presents a preliminary investigation on applicability of Single Point Incremental Forming techniques (SPIF) to composite laminates. Initially the possibility of quickly and economically forming sheet metal moulds with complex geometry was ...
SORGENTE M, FIOROTTO M, LUCCHETTA, GIOVANNI   +2 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Measurement of electromagnetic radiation in the single point incremental forming of AA3003-O

International Journal of Lightweight Materials and Manufacture, 2020
The strength and rigidity of the metals depends upon its crystal structures and intermolecular arrangement which resist its failure during loading. During the plastic deformation it is observed that an electromagnetic radiation (EMR) is emitted when ...
Manish Oraon, Vinay Sharma
doaj   +1 more source

Predicting Intermediate Shapes for Single-Point Incremental Forming [PDF]

, 2017
The work undertaken in this project presents a new computational model capable of predicting the geometry of intermediate shapes required to successfully manufacture a surface using single-point incremental forming (SPIF). The model predicts intermediate shapes by modelling the SPIF forming process in reverse, working backwards from the final desired ...
openaire   +3 more sources

Forming behavior of paperboard in single point incremental forming

BioResources, 2019
An increased demand for sustainable materials has led to intensive research in the field of three-dimensional paperboard forming. To date, this work has focused on forming processes with shape-giving tools. However, individual shapes are often required, especially for large-format products.
Philipp Stein, Wilken Franke, Magnus von Elling, Peter Groche   +3 more
openaire   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source