Results 151 to 160 of about 8,327,673 (288)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Statement concerning sword of General Manuel Armijo

, 1884
Statement concerning the military sword of General Manuel Armijo, Governor of New Mexico, which was apparently given, sold to Ritch, perhaps for the Historical Society of New Mexico, as written by Manuel S. Salazar, Santa Fe, a relative of Jose Francisco

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Indian expert consensus on prophylactic incisional single-use negative pressure wound therapy in hip and knee arthroplasty: A modified Delphi study. [PDF]

SICOT J
Bagaria V, Tapasvi S, Tiwari A.
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Statement concerning stolen animals

Statement from John Greiner, concerning the horses and mules stolen from Ambrosio of Isleta Pueblo, from his corral along the Rio Grande near the Pueblo. Made through an interpreter. Ambrosio saw the stolen animals in Santa Ana Pueblo, in possession of a

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Based on a Single Case, Cardiopulmonary Training Cannot Be Recommended as Therapy for Hemiparesis in MELAS With Ischemic Stroke. [PDF]

Kaohsiung J Med Sci
Mehri S, Finsterer J.
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Corrigendum: The association between blastocyst quality and perinatal outcomes during a single frozen-thawed blastocyst transfer cycles: a propensity score-matched study. [PDF]

Reprod Dev Med
Wu J, Yang C, Zheng W, Cao MY, Li MN, Kuang YH, Ren BN, Zu RW, Shen R, Han JY, Li PX, Guan YC.   +11 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

April 2025 BNNB Statement

The April 2025 BNNB for Lusaka stood at K11,417.99 for a family of five, reflecting a minor reduction of K128.79 from the previous month. While slight decreases were recorded in both food and non-food components—largely due to seasonal factors—this cost ...
Musosa, Edward
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