Results 91 to 100 of about 58,516 (285)

TrxR2 Lactylation Facilitates Mitochondrial Protection and Endothelial Ferroptosis Resistance in Diabetic Cardiomyopathy

Advanced Science, EarlyView.
TrxR2 deletion in diabetic mice suppresses TUFM‐AMPK‐FUNDC1‐dependent mitophagy in endothelial cells, resulting in SCP2 upregulation and mitochondrial translocation of ACSL4. Mitochondrial ACSL4 promotes mitochondrial eicosanoid biosynthesis and ferroptosis, thereby aggravating cardiac microvascular injury and diabetic cardiomyopathy.
Su Li, Muyin Liu, Chao Chen, Xinyan Li, Xiaopei Yan, Wentao Zhu, Wenyan Qiu, Qiyu Li, Xiangyu Sun, Chao Huang, Ming Yin, Zhangwei Chen, Yao Lu, Junbo Ge, Xiangqing Kong, Juying Qian, Yuqiong Chen   +16 more
wiley   +1 more source

Development of a PC interfaced blood pressure meter (E-BPMS) [PDF]

, 2008
Blood pressure is one of the fundamental vital signs, and its measurement is of great importance to medical professionals and the general public alike.
Mustapha, Baharuddin
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Practice importance of the results of population studies 
on the single umbilical artery [PDF]

РМЖ. Мать и дитя, 2020
Yu.V. Trusov, V.A. Kramarskiy, N.I. Faizullina Irkutsk State Medical Academy of Professional Education — Branch of the Russian Medical Academy of Continuous Professional Education, Irkutsk, Russian Federation This paper discusses the ...
Yu.V. Trusov, V.A. Kramarskiy, N.I. Faizullina   +2 more
doaj  

Semiconducting Polymer Nanoparticles Enable Light‐Controlled Bidirectional Modulation of Nitric Oxide in Endothelial Cells

Advanced Science, EarlyView.
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli, Andrea Pianetti, Elena Mancinelli, Anthea Villano, Matteo Vailati, Paola Lagonegro, Miryam Criado‐Gonzalez, Montserrat Climent, Hansel Comas‐Rojas, Leonardo Elia, Francesco Moccia, Gabriele Tullii, Maria Rosa Antognazza   +12 more
wiley   +1 more source

Direction of Umbilical Cord Twist and its Characteristics – a Pilot Study

International Journal of Medical Students, 2013
Background: A right-sided umbilical cord twist is associated with the presence of a single umbilical artery, congenital malformations and placenta praevia. Methods: It was an observational study. Data was collected from 137 umbilical cords, all from live
Althea V. Pinto, Alex X. Chakiath, Prudhvi Dasari, Vilekith Reddy, Shirley George, Nachiket Shankar   +5 more
doaj   +3 more sources

Fetal-derived trophoblast use the apoptotic cytokine tumor necrosis factor-alpha-related apoptosis-inducing ligand to induce smooth muscle cell death. [PDF]

, 2007
Remodeling of the uterine spiral arteries during pregnancy transforms them from high to low resistance vessels that lack vasoconstrictive properties. This process is essential to meet the demand for increased blood flow imposed by the growing fetus. Loss
Aplin, JD, Baker, PN, Cartwright, JE, Freeman, A, Harris, LK, Keogh, RJ, Whitley, GS   +6 more
core   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

A stochastic model for early placental development [PDF]

, 2013
In the human, placental structure is closely related to placental function and consequent pregnancy outcome. Studies have noted abnormal placental shape in small-for-gestational age infants which extends to increased lifetime risk of cardiovascular ...
Collins, S.L, Cotter, S. L., Heazell, A. E. P., Kimpton, L.S., Klika, V.   +4 more
core   +1 more source

MicroRNA-24 regulates vascularity after myocardial infarction [PDF]

, 2011
BACKGROUND: Myocardial infarction leads to cardiac remodeling and development of heart failure. Insufficient myocardial capillary density after myocardial infarction has been identified as a critical event in this process, although the underlying ...
Bauersachs, J., Brand, T., Engelhardt, S., Ertl, G., Fiedler, J., Galuppo, P., Gupta, S. K., Hartmann, D., Heineke, J., Jazbutyte, V., Kirchmaier, B. C., Kneitz, S., Lorenzen, J., Loyer, X., Martin, U., Pena, J., Schulte-Merker, S., Sohn-Lee, C., Soutschek, J., Thum, T., Tuschl, T.   +20 more
core   +3 more sources