Innovative solutions for lossy nonlinear transmission lines model using a modified extended mapping approach with fractional effects. [PDF]
Hussein HH, Alexan W, Kandil SA.
europepmc +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Modulation instability analysis and deriving soliton solutions of new nonlocal Lakshmanan-Porserzian-Daniel equation. [PDF]
Rabie WB, Abbas W, Ramadan ME, Ahmed HM.
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ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao +16 more
wiley +1 more source
Genotype-fitness mapping of adaptive mutants reveals shifting low-dimensional structure across divergent environments. [PDF]
Ghosh OM, Kinsler G, Good BH, Petrov DA.
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Mid‐infrared optoacoustic microscopy (MiROM) acquires lipid‐ and protein‐ associated vibrational contrast in intact fat tissue without dyes, preserving native tissue architecture. Through lateral and axial segmentation, MiROM tracks intrinsic intracellular changes during postnatal remodeling. A quantitative spatial analysis tool (Q‐SAT) maps white‐ and
Myeongseop Kim +7 more
wiley +1 more source
Relaxed Boundary Conditions in Poisson-Nernst-Planck Models: Identifying Critical Potentials for Multiple Cations. [PDF]
Liu X +4 more
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To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu +6 more
wiley +1 more source
Analytical construction and visualization of nonlinear waves in the (2+1) dimensional Kadomtsev-Petviashvili-Sawada-Kotera-Ramani equation with stability analysis. [PDF]
Ahmed M, Ahmed HM, Badra N, Samir I.
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