Results 121 to 130 of about 733,513 (333)

Refractory Status Epilepticus Treated With Bilateral Pulvinar Deep Brain Stimulation—A Case Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT New‐onset refractory status epilepticus (NORSE) arises without an identifiable cause or prior epilepsy history, with a 16%–27% mortality rate and significant long‐term neurological sequelae. Neuromodulation such as deep brain stimulation (DBS) targeting the anterior and centromedian thalamic nuclei has shown promise when the traditional ...
Mengxuan Tang   +16 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Solution of an Initial Boundary Value Problem for a Multidimensional Fourth-Order Equation Containing the Bessel Operator

open access: yesMathematics
In the present work, the transmutation operator approach is employed to construct an exact solution to the initial boundary-value problem for multidimensional free transverse equation vibration of a thin elastic plate with a singular Bessel operator ...
Shakhobiddin Karimov, Yorkinoy Tulasheva
doaj   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian   +9 more
wiley   +1 more source

Certifying solutions to overdetermined and singular polynomial systems\n over Q [PDF]

open access: green, 2014
Tulay Ayyildiz Akoglu   +2 more
openalex   +1 more source

Unconventional Solution of Singular Integral Equations

open access: yesJournal of Integral Equations and Applications, 1992
The author considers the singular integral equation \[ au(x)+(b/\pi)\int_{-1}^ 1 u(y)(y-x)^{-1} dy+\int_{-1}^ 1 k(x,y)u(y)dy=f(x), \qquad x\in(-1,1),\tag{1} \] where \(a\) and \(b\) are real constants satisfying \(a>0\), \(a^ 2+b^ 2=1\), and the index of equation (1) is \(-1\).
openaire   +3 more sources

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