Results 111 to 120 of about 3,020,455 (306)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Singularities of solutions to partial differential equations in a complex domain
Electronic Journal of Differential Equations, 2016 We give an explicit representation of the solution of the following singular Cauchy problem with analytic data, $$ u_{tt}-xu_{xx}+Cu_{x}-B(t^2-4x)^{-1}u=0. $$ We also study the singularities of this solution.
Naouel Bentiba
doaj
Results in PhysicsThis work aims to construct some novel exact solutions of the (2 + 1)-dimensional Sawada-Kotera equation (SKE). First, the resonant multiple soliton solutions (RMSSs) are discussed by employing the weight algorithm (WA) and linear superposition principle
Chunlin Chai, Kang-Jia Wang
doaj +1 more source
Stochastic dynamics with singular lower order terms in finite and infinite dimensions [PDF]
, 2009 Jin P. Stochastic dynamics with singular lower order terms in finite and infinite dimensions. Bielefeld (Germany): Bielefeld University; 2009.In this work, we aim to study several stochastic dynamics with singular coefficients.
Jin, Peng
core
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Positive and Dead-Core Solutions of Two-Point Singular Boundary Value Problems with ϕ-Laplacian
Advances in Difference Equations, 2010 The paper discusses the existence of positive solutions, dead-core solutions, and pseudo-dead-core solutions of the singular problem (ϕ(u′))′=λf(t,u,u′), u(0)-αu′(0)=A, u(T)+βu′(0)+&#
Svatoslav Staněk
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Exact behavior of singular solutions to Protter's problem with lower order terms
Electronic Journal of Differential Equations, 2012 For the (2+1)-D wave equation Protter formulated (1952) some boundary value problems which are three-dimensional analogues of the Darboux problems on the plane. Protter studied these problems in a 3-D domain, bounded by two characteristic cones and by
Aleksey Nikolov, Nedyu Popivanov
doaj
Existence for Singular Periodic Problems: A Survey of Recent Results
Abstract and Applied Analysis, 2013 We present a survey on the existence of periodic solutions of singular differential equations. In particular, we pay our attention to singular scalar differential equations, singular damped differential equations, singular impulsive differential ...
Jifeng Chu +2 more
doaj +1 more source
Singular Solutions for Shallow Cylindrical Shells
, 1973 Using solutions obtained by separation of variables, the set of singular solutions of the shallow cylindrical shell equation is completed by finding a particular integral of a second-order problem.
Doré, Roland +3 more
core +1 more source