Results 31 to 40 of about 84,927 (259)

Combining experimental and numerical analysis to estimate stress fields along the surface crack front [PDF]

open access: yesFracture and Structural Integrity, 2013
Combining experimental and computational method for determination of the singular and the non-singular stress terms along the front of the 3D surface crack is proposed.
A.S. Chernyatin   +2 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Quine on Identity

open access: yesPrincipia: An International Journal of Epistemology, 2003
In a first section, we discuss Quine’s claim according to which identity is a logical notion. We point out that Quine mixes up various types of identities: trivial (or diagonal) identity, Leibniz identity, etc.; and this leads him to commit several ...
Jean-Yves Béziau
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Heavy Hands, Magic, and Scene-Reading Traps

open access: yesEuropean Journal of Analytic Philosophy, 2007
This is one of a series of articles in which I examine errors that philosophers of language may be led to make if already prone to exaggerating the rôle compositional semantics can play in explaining how we communicate, whether by expressing propositions
Stephen Neale
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Phase-field model with concentrating-potential terms on the boundary

open access: yesResults in Applied Mathematics
In this paper we analyze a generalization of the semilinear phase field model from G. Caginalp (1986, 1991) and A. Jiménez-Casas-A. Rodriguez-Bernal (1996, 2005), where we consider a singular term concentrated in a neighborhood of Γ, the boundary of ...
Ángela Jiménez-Casas
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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