Results 11 to 20 of about 343 (188)

On the geometric interpretation of seminormality [PDF]

open access: yes, 1978
We give a new characterization of the property of seminormality for 1-dimensional local rings; and with the help of this result we develop extensions of the theorems of Salmon and Bombieri which interpret this property in terms of singularities of ...
Edward D. Davis
core   +1 more source

The symmetric signature [PDF]

open access: yes, 2017
We define two related invariants for a d-dimensional local ring (R,,k) called syzygy and differential symmetric signature by looking at the maximal free splitting of reflexive symmetric powers of two modules: the top-dimensional syzygy module SyzdR(k) of
Brenner H., Caminata A.
core   +1 more source

Grothendieck-Serre in the split unramified case [PDF]

open access: yes, 2022
28 pagesInternational audienceThe Grothendieck-Serre conjecture predicts that every generically trivial torsor under a reductive group scheme $G$ over a regular local ring $R$ is trivial.
Česnavičius, Kęstutis
core  

Curve singularities with one Puiseux pair and value sets of modules over their local rings

open access: yesJournal of Algebraic Combinatorics
v3: Theorem 3.4 in v2 has been eliminated as a result of a gap in the proof. Section 3.2 in v2 has been eliminated. The rest of main results remain unchanged. General redaction has been improved. v1: Comments are very welcome! 19 pages.
Alberich Carramiñana, Maria   +2 more
openaire   +8 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Semistable reduction of modular curves associated with maximal subgroups in prime level [PDF]

open access: yes, 2019
We complete the description of semistable models for modular curves associated with maximal subgroups of $\mathrm{GL}_2 ({\mathbb F}_p )$ (for $p$ any prime, $p>5$).
Parent, Pierre, Edixhoven, Bas
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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