Results 121 to 130 of about 73,706 (315)

Numerical analysis of symmetrical and asymmetrical reinforced concrete flat slabs - an integrated slab/ column analysis

open access: yesRevista IBRACON de Estruturas e Materiais
This paper studies the modeling of symmetric and asymmetric flat slabs, presenting alternatives to the problem of singularity encountered when the slab is modeled considering columns as local support.
A. Puel, D. D. Loriggio
doaj   +1 more source

An Efficient FG-FFT With Optimal Replacement Scheme and Inter/Extrapolation Method for Analysis of Electromagnetic Scattering Over a Frequency Band

open access: yesIEEE Access, 2019
In this paper, the replacement values to the singularity of fitting Green's function are intensively researched in Fitting Green's function Fast Fourier Transformation (FG-FFT) for different frequency points.
Wei-Bin Kong   +5 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

qbicsoftware/qbic-singularity-snpeff: First major release

open access: yes, 2017
<p>First major release of the Singularity container with SnpEff</p ...
Sven F., Alexander Peltzer
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

sylabs/singularity: Singularity 3.0.2 release candidate 1

open access: yes, 2018
<p>Seasons greetings Singularity community!</p> <p>The Singularity elves have been hard at work and the holidays are coming a little early this year!</p> <p>:gift:</p> <p>This is a release candidate for ...
David Godlove   +29 more
core   +1 more source

Flows, transits and (dis)connection points: contributions towards a critical Lusophony

open access: yesComunicação e Sociedade, 2018
As a concept, Lusophony is today looked upon with justified suspicion by many Portuguese-speaking people. It is impossible to separate this concept from the colonial ballast that bounds the countries that have Portuguese as the official language. However,
Luís Cunha   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

housw/Bioinfo-Singularity: first pre-release

open access: yes, 2019
<p>This is a first pre-release of Bioinfo-Singularity</p ...
Shengwei Hou
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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