The biomechanical effect of different spring extension assist mechanisms in mechanical 4-bar polycentric prosthetic knees for unilateral above/through-knee amputees. [PDF]
Toderita D +5 more
europepmc +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
A neural poly-vector based non-orthogonal frame field generation method for quad meshing. [PDF]
Yu Y, Li N, Gong G, Lin X.
europepmc +1 more source
Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro +8 more
wiley +1 more source
Tailoring Topological Magnetic States in Multilayer Nanostructures: Bloch Points, Chiral Bobbers, and Skyrmion Tubes. [PDF]
Gareeva Z +3 more
europepmc +1 more source
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Atemporality from Conservation Laws of Physics in Lorentzian-Euclidean Black Holes. [PDF]
De Bianchi S, Capozziello S, Battista E.
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Topological-charge multiplexed metasurfaces for generating structural acoustic field and remote dynamic control. [PDF]
Quan J +11 more
europepmc +1 more source

