Results 51 to 60 of about 23,028 (249)

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Dozy-Chaos Mechanics for a Broad Audience

open access: yesChallenges, 2020
A new and universal theoretical approach to the dynamics of the transient state in elementary physico-chemical processes, called dozy-chaos mechanics (Egorov, V.V. Heliyon Physics2019, 5, e02579), is introduced to a wide general readership.
Vladimir V. Egorov
doaj   +1 more source

A Physical – Geometrical Model of an Early Universe [PDF]

open access: yesINCAS Bulletin, 2014
A physical-geometrical model for a possible early universe is proposed. One considers an initial singularity containing the energy of the whole universe. The singularity expands as a spherical wave at the speed of light generating space and time.
Corneliu BERBENTE
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

On Legendrian Singularities [PDF]

open access: yesProceedings of the American Mathematical Society, 1987
We introduce three natural equivalence relations among Legendrian singularities and study their properties by using recent results of the theory of singularities of smooth map germs.
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Kinematics and Singularity Analysis of an Underwater Electric Manipulator

open access: yesKongzhi Yu Xinxi Jishu, 2023
An underwater electric manipulator is a key operational tool for unmanned underwater vehicles. The control of this manipulator demands kinematic models, but for arms of different structures, these models differ.
HUANG Zhong, LIU Kean
doaj  

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