Results 81 to 90 of about 23,028 (249)
Singularity categories and singular loci of certain quotient singularities
Let $V$ be a finite dimensional $k$-vector space, where $k$ is an algebraic closed field of characteristic zero. Let $G \subseteq \mathrm{SL}(V)$ be a finite abelian group, and denote by $S$ the $G$-invariant subring of the polynomial ring $k[V]$. It is shown that the singularity category $D_{sg}(S)$ recovers the reduced singular locus of $\mathrm{Spec}
Chen, Xiaojun, Zeng, Jieheng
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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Қарағанды университетінің хабаршысы. Математика сериясы, 2020 The possibilities of constructing inhomogeneous system solutions for partial differential equations of the third order have been studied. The construction of general and particular solutions corresponding to homogeneous system comprehensively ...
Zh.N. Tasmambetov, Zh.K. Ubayeva
doaj
On the application of Sturm's theorem to analysis of dynamic pull-in for a graphene-based MEMS model
Applied and Computational Mechanics, 2018 A novel procedure based on the Sturm’s theorem for real-valued polynomials is developed to predict and identify periodic and non-periodic solutions for a graphene-based MEMS lumped parameter model with general initial conditions.
Omarov D. +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
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Progress in Biophysics and Molecular Biology, 2019 The feasibility of formulating the Singularity of Nature was enunciated by Einstein's mathematical formula, demonstrating the equivalency of energy and mass (E = mc2). Despite that statement of principle, it has proven impossible to achieve this goal scientifically by directly merging biology and physics into one continuum.
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Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
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Revista IBRACON de Estruturas e MateriaisThis paper studies the modeling of symmetric and asymmetric flat slabs, presenting alternatives to the problem of singularity encountered when the slab is modeled considering columns as local support.
A. Puel, D. D. Loriggio
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