Results 81 to 90 of about 581,282 (341)

Exemplarité et singularité dans le champ politique. Les livres des politiques

open access: yesTracés, 2018
Since the 1990s, the norm of singularity has been spreading across the political field. The purpose of this paper is to analyze a specific object: the political book. The careful examination of 210 publications from the 1958-2011 period makes it possible
Christian Le Bart
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Le populaire et le singulier. La singularité de l’acte créateur face au rôle social du théâtre (1945-1980)

open access: yesTracés, 2018
This article analyzes the process of artistic singularization that characterized French public theatre between the post-war period and the beginning of the 1980s.
Marjorie Glas
doaj   +1 more source

Reeb orbits and the minimal discrepancy of an isolated singularity [PDF]

open access: yes, 2014
Let A be an affine variety inside a complex N dimensional vector space which has an isolated singularity at the origin. The intersection of A with a very small sphere turns out to be a contact manifold called the link of A.
Mark McLean
semanticscholar   +1 more source

SINGULAR HERMITIAN METRICS WITH ISOLATED SINGULARITIES

open access: yesNagoya Mathematical Journal, 2022
AbstractIn this paper, we study the coherence of a higher rank analogue of a multiplier ideal sheaf. Key tools of the study are Hörmander’s $L^2$ -estimate and a singular version of a Demailly–Skoda-type result.
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Conjuguer singularité et conformité pour se positionner sur le marché international de l'urbain. Confluence et le renouvellement de l'image de Lyon

open access: yesConfins, 2018
To attract the investors for whom they compete in the urban market, cities aim after making themselves desirable for national and global capital seeking locations to increase profitability. Thus, they work to improve their brand image.
Matthieu Adam, Georges-Henry Laffont
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

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