Results 81 to 90 of about 73,706 (315)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Arboreal singularities [PDF]

open access: yesGeometry & Topology, 2017
32 pages; 2 figures; to appear in Geometry & ...
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

sylabs/singularity: SingularityCE 3.11.4

open access: yes, 2023
SingularityCE 3.11.4 is a patch release in the 3.11 series, with changes detailed below. Changed defaults / behaviours Add xino=on mount option for writable kernel overlay mount points to fix inode numbers consistency after kernel cache flush.
Dave Trudgian   +27 more
core   +1 more source

Removing singularities [PDF]

open access: yesJournal of High Energy Physics, 2003
Big bang/crunch curvature singularities in exact CFT string backgrounds can be removed by turning on gauge fields. This is described within a family of {SL(2)xSU(2)xU(1)_x}/{U(1)xU(1)} quotient CFTs. Uncharged incoming wavefunctions from the ``whiskers'' of the extended universe can be fully reflected if and only if a big bang/crunch curvature ...
Elitzur, Shmuel   +2 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

singularityware/singularity: Singularity 2.6.0 Release Candidate 1

open access: yes, 2018
<p>Greetings Singularity-ers!</p> <p>I'm excited to announce the second release candidate for the 2.6 branch! This release candidate has a bug fix and lot of cool new features.</p> <p>Please test it in your environments when
George Hartzell   +29 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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