Results 71 to 80 of about 17,380,414 (202)

Attenuation of arsenic trioxide‐induced endothelial injury: unveiling the protective role of ginkgolic acid through inhibition of TRPM4 SUMOylation: Evidence from Raman cellular imaging

open access: yesVIEW, Volume 7, Issue 1, February 2026.
Inhibiting the SUMOylation modification of TRPM4 can prevent the vascular endothelial damage caused by ATO. Inhibition of TRPM4 SUMOylation, either pharmacologically by GA or genetically by the K618R mutation, protects against ATO‐induced vascular endothelial damage.
Ting‐Ting Tong   +18 more
wiley   +1 more source

Automatic Adaptive and Targeted Localized Refinement in Transient Structural Dynamic Simulations Using the Multiresolution Finite Wavelet Domain Method

open access: yesInternational Journal for Numerical Methods in Engineering, Volume 127, Issue 1, 15 January 2026.
ABSTRACT The multiresolution finite wavelet domain method has been meticulously studied in numerous wave propagation simulations, showing excellent convergence properties and very fast computing times. The multiresolution procedure always starts with the coarse solution, and then finer solutions can be superimposed on the coarse solution until ...
Dimitris Dimitriou   +2 more
wiley   +1 more source

Numerical treatment of singular perturbation problems exhibiting dual boundary layers

open access: yesAin Shams Engineering Journal, 2015
In this paper, we employed a fitted operator finite difference method on a uniform mesh for solving singularly perturbed two-point boundary value problems exhibiting dual boundary layers.
K. Phaneendra   +2 more
doaj   +1 more source

Exploring the Fecal Microbiome Dysbiosis and Its Plasma Metabolome Determinants in Advanced Parkinson's Disease With Motor Complications

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Our multiomics analysis across three PD cohorts revealed distinct fecal microbiome and plasma metabolome alterations in patients with motor complications (PD‐MC). We identified specific microbial and metabolic biomarkers and uncovered significant correlations between them, providing new insights into PD‐MC pathophysiology. ABSTRACT Background Parkinson'
Shuangjie Qian   +11 more
wiley   +1 more source

A stochastic numerical approach for a class of singular singularly perturbed system. [PDF]

open access: yesPLoS One, 2022
Sabir Z   +4 more
europepmc   +1 more source

Singularly perturbed stochastic systems [PDF]

open access: yesUkrainian Mathematical Journal, 1997
Summary: Problems of the singular perturbation of reducible invertible operators are classified and their applications to the analysis of stochastic Markov systems represented by random evolutions are considered. The phase merging, averaging, and diffusion approximation schemes are discussed for dynamical systems with rapid Markov switchings.
openaire   +3 more sources

Analytical Solutions and Computer Modeling of a Boundary Value Problem for a Nonstationary System of Nernst–Planck–Poisson Equations in a Diffusion Layer

open access: yesMathematics
This article proposes various new approximate analytical solutions of the boundary value problem for the non-stationary system of Nernst–Planck–Poisson (NPP) equations in the diffusion layer of an ideally selective ion-exchange membrane at overlimiting ...
Savva Kovalenko   +4 more
doaj   +1 more source

Singular Perturbation of Nonlinear Systems with Regular Singularity

open access: yesDiscrete Dynamics in Nature and Society, 2018
We extend Balser-Kostov method of studying summability properties of a singularly perturbed inhomogeneous linear system with regular singularity at origin to nonlinear systems of the form εzf′=Fε,z,f with F a Cν-valued function, holomorphic in a polydisc
Domingos H. U. Marchetti   +1 more
doaj   +1 more source

CONTROLLABILITY OF ESSENTIALLY VARIOUS-SPEED SINGULARLY PERTURBED DYNAMIC SYSTEMS

open access: yesНаука и техника, 2013
The paper considers the controllability problem of essentially various-speed singularly perturbed dynamic system consisting of three subsystems of different dimensions, containing a small parameter to a variable degree as a multiplier for derivatives ...
T. B. Kopeikina, A. V. Grekova
doaj  

On transformation to the singularly perturbed system

open access: yesJournal of Physics: Conference Series, 2011
A rapid progress in hard- and software development of computational facilities as well as in numerical methods has increased the role of numerical simulations in the quantitative system analysis of many engineering problems. At the same time, the system complexity (in terms of dimensionality and non-linearity) has grown considerably increasing demand ...
openaire   +3 more sources

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