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Reconstruction of the human sinoatrial node
The Anatomical Record, 1967AbstractThe superior vena cava and adjacent right atrium containing the sinoatrial node in each of five human hearts was studied histologically in serial section. The tissue block of a 41 year old man was reconstructed in four colors to provide a three‐dimensional model of the sinoatrial node, atrial relations, blood supply and nodal configuration. The
Raymond C. Truex +2 more
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Cardiovascular Drugs and Therapy, 1988
The sinoatrial node (SAN) was discovered in 1906 by Keith and Flack. The relation between its ultrastructure and function was first studied by Trautwein and Uchizono in 1963, whereas this relation was definitely established by Taylor and coworkers in 1978. The impulse originates from cells with a relatively low percentage of myofilaments.
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The sinoatrial node (SAN) was discovered in 1906 by Keith and Flack. The relation between its ultrastructure and function was first studied by Trautwein and Uchizono in 1963, whereas this relation was definitely established by Taylor and coworkers in 1978. The impulse originates from cells with a relatively low percentage of myofilaments.
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Functional morphology of the pig sinoatrial node
Journal of Molecular and Cellular Cardiology, 1987The porcine sinoatrial node in an isolated right atrium preparation is characterized by unifocal impulse generation. It has a rather elongated shape and the larger part of its volume is taken up by collagen and fibroblasts. The impulse appears to emerge from a site where the percentage of myofilaments is relatively low. The impulse is propagated faster
Berend de Jonge +3 more
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Disturbances of Sinoatrial Node Function [PDF]
, 2000 The spectrum of human cardiac performance is amazingly broad with cardiac output varying 10–20-fold between that measured during the deepest of sleep to that seen at peak of exercise. In large part this tremendous cardiac reserve is modulated both by cardiac contractility as well as the heart rate itself.
Michael R. Lauer, Ruey J. Sung
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The Development of the Sinoatrial Node
1978In contrast to the many investigations devoted to the morphological development of the atrioventricular specialized tissues (see James, 1970; Anderson and Taylor, 1972 for review) few researchers have studied the development of the sinoatrial node. Amongst the reports existing on this subject, descriptions of the initial histological differentiation of
Ho Siew Yen +3 more
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Journal of Molecular and Cellular Cardiology, 1985
The primary pacemaker, i.e. the group of pacemaker cells discharging the sinoatrial node comprises less than 1000 cells in the guinea-pig and about 5000 cells in the rabbit. These primary pacemaker cells are described as 'central nodal' cells in light microscopy and as 'typical nodal' cells in electron microscopy.
M. Masson-Pévet +6 more
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The primary pacemaker, i.e. the group of pacemaker cells discharging the sinoatrial node comprises less than 1000 cells in the guinea-pig and about 5000 cells in the rabbit. These primary pacemaker cells are described as 'central nodal' cells in light microscopy and as 'typical nodal' cells in electron microscopy.
M. Masson-Pévet +6 more
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Parasympathetic postganglionic pathways to the sinoatrial node
American Journal of Physiology-Heart and Circulatory Physiology, 1990Vagal ganglia that innervate the canine sinoatrial node (SAN) have been localized to a fat pad overlying and surrounding the right pulmonary vein complex (PVFP). The ventral epicardial surface of the right atrium was mapped in seven dogs anesthetized with alpha-chloralose after beta-blockade (timolol) and cardiac sympathetic and parasympathetic ...
R. D. Wurster +4 more
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MDCT of the S-Shaped Sinoatrial Node Artery
American Journal of Roentgenology, 2008The purpose of this study was to use 64-MDCT to investigate the anatomic characteristics of the S-shaped variant of the sinoatrial node (SAN) artery and to describe the clinical implications of the findings in ablative procedures involving the left atrium.Coronary CT angiograms of 250 patients (152 men, 98 women; mean age, 60 +/- 12 [SD] years) were ...
Stephanie Channual +5 more
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1976
The impulse for the activation of the heart is generated normally in the sinoatrial node (SA node). This structure covers an area of only a few square millimeters. The cells have an irregular contour and are small (diameter less than 10 μ). Furthermore, they contain sparse myofilaments which are often not well organized. The intercellular junctions are
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The impulse for the activation of the heart is generated normally in the sinoatrial node (SA node). This structure covers an area of only a few square millimeters. The cells have an irregular contour and are small (diameter less than 10 μ). Furthermore, they contain sparse myofilaments which are often not well organized. The intercellular junctions are
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The pacemaker cell of the sinoatrial node of the rabbit
American Journal of Physiology-Heart and Circulatory Physiology, 1978Rabbit sinoatrial nodes were isolated and studied in an attempt to determine the cell of origin of the true pacemaker potential. Cells of the sinoatrial node of the rabbit giving rise to the characteristic true pacemaker potential were iontophoretically tagged with lanthanum.
L. S. D'Agrosa +2 more
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