Results 151 to 160 of about 42,114 (261)

Cerebral Blood and Cerebrospinal Fluid Flow Dynamics in Endurance Athletes: Associations With Aortic Recoil and Heart Rate

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 3, March 2026.
ABSTRACT Endurance training elicits profound cardiovascular adaptations, including lower heart rate (HR), greater stroke volume (SV), and enhanced aortic Windkessel function. This study aimed to investigate cerebral blood and cerebrospinal fluid (CSF) flow dynamics in endurance athletes and their relations with cardiovascular parameters.
Daisuke Hoshi   +8 more
wiley   +1 more source

Suppression of premature ventricular complexes with the PDE5 inhibitor sildenafil: First clinical experience

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 625-631, 1 March 2026.
Abstract The phosphodiesterase‐5 inhibitor sildenafil suppresses ventricular arrhythmias in a sheep model of drug‐induced long QT. In that study, ventricular arrhythmias were abolished by reducing premature ventricular complexes (PVCs) and delaying PVC onset, thus preventing ‘R‐on‐T’ ventricular tachycardia.
David C. Hutchings   +3 more
wiley   +1 more source

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 1120-1133, 1 March 2026.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson   +11 more
wiley   +1 more source

Targetable Effects of the Anesthetic, Ubiquinone‐5, on Murine Cardiac Rhythm

open access: yesThe FASEB Journal, Volume 40, Issue 4, 28 February 2026.
The novel anesthetic, ubiquinone‐5 (Ub5), causes second‐degree heart block, in part, by compromising the mitochondrial membrane potential (ΔΨ) in cardiomyocytes. Ub5‐mediated inhibition of electron transport and induction of excessive proton leak via the aspartate–glutamate carrier, Aralar, prevent mitochondria from generating and maintaining an ...
Haeun Lim   +3 more
wiley   +1 more source

Carfilzomib-induced sinus bradycardia: A case report and literature review. [PDF]

open access: yesSAGE Open Med Case Rep
Zhao X   +7 more
europepmc   +1 more source

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