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Symptomatic 5‐fluorouracil‐induced sinus bradycardia
Internal Medicine Journal, 2011Abstract5‐Fluorouracil (5‐FU) is a commonly used anti‐neoplastic agent. 5‐FU has been not uncommonly associated with cardiotoxicity, although the many potentially causative mechanisms are yet to be established. Here, we present the case of a 61‐year‐old gemstone miner who developed symptomatic sinus bradycardia while receiving a continuous 5‐FU ...
A D, Lee, M J, McKay
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Survey of Anesthesiology, 1978
ABSTRACT In the aged, sinus bradycardia represents the sinus‐node‐dysfunction component of diffuse conduction system disease associated with coronary and cerebral arteriosclerosis. Findings are presented on 15 patients whose ages ranged from 69 to 93 years at the time of admission to a home for the aged.
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ABSTRACT In the aged, sinus bradycardia represents the sinus‐node‐dysfunction component of diffuse conduction system disease associated with coronary and cerebral arteriosclerosis. Findings are presented on 15 patients whose ages ranged from 69 to 93 years at the time of admission to a home for the aged.
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Thalidomide causes sinus bradycardia in ALS
Aktuelle Neurologie, 2007Neuroinflammation contributes to motor neuron degeneration in ALS. Thalidomide (THL) shows potent anti-inflammatory properties and increased the lifespan in ALS transgenic mice. Thalidomide was therefore suggested as atherapeutic intervention for the treatment of ALS.We conducted a pilot, randomized clinical trial of THL in patients with ALS to assess ...
Thomas, Meyer +7 more
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Seckel Syndrome with Severe Sinus Bradycardia
The Indian Journal of Pediatrics, 2014Seckel syndrome is an uncommon form of microcephalic dwarfism. The authors report a young boy with Seckel syndrome who presented with severe sinus bradycardia with symptoms of syncope and presyncope. Implantation of a permanent pacemaker was necessary in view of the severe symptoms.
Chandramohan, Ramasamy +2 more
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Sinus Bradycardia After Intravenous Pulse Methylprednisolone
Pediatrics, 2007High-dose intravenous pulse methylprednisolone is an important therapeutic modality for many autoimmune conditions in both children and adults. Adverse effects of this therapy include hypertension, hyperglycemia, and, in children, behavioral changes. Cardiac rhythm disturbances, both tachyarrhythmias and bradyarrhythmias, have been reported in adults ...
Jonathan D, Akikusa +4 more
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Sinus Bradycardia in Habitual Cocaine Users
The American Journal of Cardiology, 2017Common physiological manifestations of cocaine are related to its adrenergic effects, due to inhibition of dopamine and norepinephrine uptake at the postsynaptic terminal. Few studies have documented bradycardia secondary to cocaine use, representing the antithesis of its adrenergic effects.
Sona M, Franklin +2 more
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Bradycardia: sinus and AV node dysfunction
Herzschrittmachertherapie + Elektrophysiologie, 2015The surface electrocardiogram (ECG) holds many clues with regard to the etiology of bradycardia and site of atrioventricular (AV) block. Bedside maneuvers may prove helpful in cases of 2:1 AV block or situations where the data is not all concordant. Wenckebach conduction may occur in any region of the heart, and there are nonpathologic mimickers of ...
Cara N, Pellegrini, Melvin M, Scheinman
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SINUS BRADYCARDIA IN ACUTE RHEUMATIC FEVER
Annals of Internal Medicine, 1952Excerpt INTRODUCTION Sinus tachycardia is widely recognized as one of the classic features of active rheumatic fever, but the fact that an abnormally slow heart rate is often present during the acu...
J G, HIRSCH, D M, FLETT
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Profound Sinus Bradycardia After Intravenous Nicardipine
Anesthesia & Analgesia, 2002Nicardipine-induced bradycardia has been reported in experimental animals but not in clinical patients. We report a clinical case of unexpected bradycardia caused by nicardipine. The mechanism of this bradycardia was not clear, and depression of sympathetic tone by epidural anesthesia, hypothermia, and paroxysmal atrial fibrillation might have been ...
Hajime, Arima +5 more
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Asymptomatic Sinus Bradycardia Following Bariatric Surgery
The American Journal of Cardiology, 2014Approximately 121,000 bariatric surgical procedures are performed annually, and salutary effects include a reduction in cardiovascular morbidity and mortality, risk factor modification, and improvement in sympathovagal tone. There are anecdotal accounts of unexplained sinus bradycardia (SB) after significant weight loss but no systematic studies have ...
Manish G, Malik +4 more
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