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Thalidomide causes sinus bradycardia in ALS [PDF]

open access: possibleAktuelle Neurologie, 2007
Neuroinflammation contributes to motor neuron degeneration in ALS. Thalidomide (THL) shows potent anti-inflammatory properties and increased the lifespan in ALS transgenic mice. Thalidomide was therefore suggested as atherapeutic intervention for the treatment of ALS.We conducted a pilot, randomized clinical trial of THL in patients with ALS to assess ...
Nadja Borisow   +7 more
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Sinus bradycardia with hiatus hernia

American Heart Journal, 1977
Three cases of large mixed sliding and paraesophageal hiatus hernias are described. These were associated with episodes of sinus bradycardia. The bradycardia was abolished by atropine pointing to vagal mediation. After surgical repair of the hernia there was no recurrence of the arrhythmia.
J.G.B. Thurston, Peter W. Marks
openaire   +3 more sources

Thalidomide-Induced Sinus Bradycardia

Annals of Pharmacotherapy, 2003
OBJECTIVE: To report a case of thalidomide-induced sinus bradycardia in an elderly man. CASE SUMMARY: A 72-year-old white man, with transfusion-dependent refractory anemia with ringed sideroblasts and hypertension treated with atenolol, was started on thalidomide 100 mg at bedtime.
Susan S Yu   +3 more
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Sinus Bradycardia in the Aged

Survey of Anesthesiology, 1978
ABSTRACTIn the aged, sinus bradycardia represents the sinus‐node‐dysfunction component of diffuse conduction system disease associated with coronary and cerebral arteriosclerosis. Findings are presented on 15 patients whose ages ranged from 69 to 93 years at the time of admission to a home for the aged.
openaire   +4 more sources

Fetal Bradycardia and Sinus Node Dysfunction [PDF]

open access: possiblePediatric Cardiology, 2012
The study reported here is a rare case of fetal sinus bradycardia that evolved into symptomatic bradycardia after birth, at which time the implantation of a cardiac pacemaker was indicated. Fetal echocardiography was used to diagnose the type of cardiac rhythm that caused the intra-uterine bradycardia, which enabled the initiation of the appropriate ...
openaire   +2 more sources

Seckel Syndrome with Severe Sinus Bradycardia

The Indian Journal of Pediatrics, 2014
Seckel syndrome is an uncommon form of microcephalic dwarfism. The authors report a young boy with Seckel syndrome who presented with severe sinus bradycardia with symptoms of syncope and presyncope. Implantation of a permanent pacemaker was necessary in view of the severe symptoms.
Santhosh Satheesh   +2 more
openaire   +2 more sources

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