Results 261 to 270 of about 563,198 (309)

Amustaline/glutathione pathogen‐reduced red cell hemoglobin utilization in complex cardiac surgery: A post hoc analysis of the phase 3 ReCePI trial

open access: yesTransfusion, EarlyView.
Abstract Background The ReCePI randomized, controlled trial compared amustaline/glutathione pathogen‐reduced (PR) and conventional red blood cell (RBC) transfusions in cardiac surgery. Study design and methods We performed a post‐hoc analysis of hemoglobin (Hb) utilization and safety outcomes.
Ian J. Welsby   +11 more
wiley   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

open access: yesExperimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng   +1 more
wiley   +1 more source

Systolic‐dominant coronary flow in rats and mice: Challenging the diastolic paradigm across conscious and anaesthetized states

open access: yesExperimental Physiology, EarlyView.
Abstract Extensive research in humans, dogs, rabbits, rats, mice and other mammals has consistently demonstrated that coronary blood flow (CBF) peaks during ventricular diastole. For example, studies using transthoracic Doppler echocardiography in anaesthetized rats and mice, isolated blood‐perfused rat hearts and Doppler probes sutured to the ...
Heidi L. Lujan   +2 more
wiley   +1 more source

Atrial fibrillation, sinoatrial and atrioventricular node dysfunction in a mouse model of heart failure with preserved ejection fraction

open access: yesExperimental Physiology, EarlyView.
Summary of the timeline of characterized events related to atrial fibrilation (AF) and diastolic dysfunction in a mouse heart failure with preserved ejection fraction (HFpEF) model. Three weeks after the initiation of the diet regimen with high fat diet (HFD) and Nω‐nitro‐l‐arginine methyl ester (l‐NAME) in drinking water to induce HFpEF, significantly
Bernadin Ndongson‐Dongmo   +2 more
wiley   +1 more source

Suppression of premature ventricular complexes with the PDE5 inhibitor sildenafil: First clinical experience

open access: yesExperimental Physiology, EarlyView.
Abstract The phosphodiesterase‐5 inhibitor sildenafil suppresses ventricular arrhythmias in a sheep model of drug‐induced long QT. In that study, ventricular arrhythmias were abolished by reducing premature ventricular complexes (PVCs) and delaying PVC onset, thus preventing ‘R‐on‐T’ ventricular tachycardia.
David C. Hutchings   +3 more
wiley   +1 more source

On the Potential of Large Language Models in ECG-based AFib and Sinus Rhythm Detection and Justification

open access: diamond
Mehdi Slim   +8 more
openalex   +2 more sources

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

open access: yesExperimental Physiology, EarlyView.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson   +11 more
wiley   +1 more source

Glial cells in the heart: Implications for their roles in health and disease

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya   +2 more
wiley   +1 more source

Kawasaki Disease Shock Syndrome With Progressive AV Block and Atrioventricular Dissociation: Case Report

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Chengjun Dai   +6 more
wiley   +1 more source

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